Nop9 is a PUF-like protein that prevents premature cleavage to correctly process pre-18S rRNA
Nop9 is a conserved small ribosomal subunit biogenesis factor. Here, Zhang et al. show that Nop9, in complex with RNA, adopts a C-shaped fold formed from 11 Pumillo repeats and propose that Nop9 inhibits premature cleavage of 20S pre-rRNA by inhibiting the Nob1 nuclease.
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Nature Portfolio
2016
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oai:doaj.org-article:faa28510bd764afbbb1cc91b25bbfcb82021-12-02T14:39:29ZNop9 is a PUF-like protein that prevents premature cleavage to correctly process pre-18S rRNA10.1038/ncomms130852041-1723https://doaj.org/article/faa28510bd764afbbb1cc91b25bbfcb82016-10-01T00:00:00Zhttps://doi.org/10.1038/ncomms13085https://doaj.org/toc/2041-1723Nop9 is a conserved small ribosomal subunit biogenesis factor. Here, Zhang et al. show that Nop9, in complex with RNA, adopts a C-shaped fold formed from 11 Pumillo repeats and propose that Nop9 inhibits premature cleavage of 20S pre-rRNA by inhibiting the Nob1 nuclease.Jun ZhangKathleen L. McCannChen QiuLauren E. GonzalezSusan J. BasergaTraci M. Tanaka HallNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016) |
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Science Q Jun Zhang Kathleen L. McCann Chen Qiu Lauren E. Gonzalez Susan J. Baserga Traci M. Tanaka Hall Nop9 is a PUF-like protein that prevents premature cleavage to correctly process pre-18S rRNA |
description |
Nop9 is a conserved small ribosomal subunit biogenesis factor. Here, Zhang et al. show that Nop9, in complex with RNA, adopts a C-shaped fold formed from 11 Pumillo repeats and propose that Nop9 inhibits premature cleavage of 20S pre-rRNA by inhibiting the Nob1 nuclease. |
format |
article |
author |
Jun Zhang Kathleen L. McCann Chen Qiu Lauren E. Gonzalez Susan J. Baserga Traci M. Tanaka Hall |
author_facet |
Jun Zhang Kathleen L. McCann Chen Qiu Lauren E. Gonzalez Susan J. Baserga Traci M. Tanaka Hall |
author_sort |
Jun Zhang |
title |
Nop9 is a PUF-like protein that prevents premature cleavage to correctly process pre-18S rRNA |
title_short |
Nop9 is a PUF-like protein that prevents premature cleavage to correctly process pre-18S rRNA |
title_full |
Nop9 is a PUF-like protein that prevents premature cleavage to correctly process pre-18S rRNA |
title_fullStr |
Nop9 is a PUF-like protein that prevents premature cleavage to correctly process pre-18S rRNA |
title_full_unstemmed |
Nop9 is a PUF-like protein that prevents premature cleavage to correctly process pre-18S rRNA |
title_sort |
nop9 is a puf-like protein that prevents premature cleavage to correctly process pre-18s rrna |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/faa28510bd764afbbb1cc91b25bbfcb8 |
work_keys_str_mv |
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