Nop9 is a PUF-like protein that prevents premature cleavage to correctly process pre-18S rRNA

Nop9 is a conserved small ribosomal subunit biogenesis factor. Here, Zhang et al. show that Nop9, in complex with RNA, adopts a C-shaped fold formed from 11 Pumillo repeats and propose that Nop9 inhibits premature cleavage of 20S pre-rRNA by inhibiting the Nob1 nuclease.

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Autores principales: Jun Zhang, Kathleen L. McCann, Chen Qiu, Lauren E. Gonzalez, Susan J. Baserga, Traci M. Tanaka Hall
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/faa28510bd764afbbb1cc91b25bbfcb8
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spelling oai:doaj.org-article:faa28510bd764afbbb1cc91b25bbfcb82021-12-02T14:39:29ZNop9 is a PUF-like protein that prevents premature cleavage to correctly process pre-18S rRNA10.1038/ncomms130852041-1723https://doaj.org/article/faa28510bd764afbbb1cc91b25bbfcb82016-10-01T00:00:00Zhttps://doi.org/10.1038/ncomms13085https://doaj.org/toc/2041-1723Nop9 is a conserved small ribosomal subunit biogenesis factor. Here, Zhang et al. show that Nop9, in complex with RNA, adopts a C-shaped fold formed from 11 Pumillo repeats and propose that Nop9 inhibits premature cleavage of 20S pre-rRNA by inhibiting the Nob1 nuclease.Jun ZhangKathleen L. McCannChen QiuLauren E. GonzalezSusan J. BasergaTraci M. Tanaka HallNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Jun Zhang
Kathleen L. McCann
Chen Qiu
Lauren E. Gonzalez
Susan J. Baserga
Traci M. Tanaka Hall
Nop9 is a PUF-like protein that prevents premature cleavage to correctly process pre-18S rRNA
description Nop9 is a conserved small ribosomal subunit biogenesis factor. Here, Zhang et al. show that Nop9, in complex with RNA, adopts a C-shaped fold formed from 11 Pumillo repeats and propose that Nop9 inhibits premature cleavage of 20S pre-rRNA by inhibiting the Nob1 nuclease.
format article
author Jun Zhang
Kathleen L. McCann
Chen Qiu
Lauren E. Gonzalez
Susan J. Baserga
Traci M. Tanaka Hall
author_facet Jun Zhang
Kathleen L. McCann
Chen Qiu
Lauren E. Gonzalez
Susan J. Baserga
Traci M. Tanaka Hall
author_sort Jun Zhang
title Nop9 is a PUF-like protein that prevents premature cleavage to correctly process pre-18S rRNA
title_short Nop9 is a PUF-like protein that prevents premature cleavage to correctly process pre-18S rRNA
title_full Nop9 is a PUF-like protein that prevents premature cleavage to correctly process pre-18S rRNA
title_fullStr Nop9 is a PUF-like protein that prevents premature cleavage to correctly process pre-18S rRNA
title_full_unstemmed Nop9 is a PUF-like protein that prevents premature cleavage to correctly process pre-18S rRNA
title_sort nop9 is a puf-like protein that prevents premature cleavage to correctly process pre-18s rrna
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/faa28510bd764afbbb1cc91b25bbfcb8
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