Nop9 is a PUF-like protein that prevents premature cleavage to correctly process pre-18S rRNA
Nop9 is a conserved small ribosomal subunit biogenesis factor. Here, Zhang et al. show that Nop9, in complex with RNA, adopts a C-shaped fold formed from 11 Pumillo repeats and propose that Nop9 inhibits premature cleavage of 20S pre-rRNA by inhibiting the Nob1 nuclease.
Guardado en:
Autores principales: | Jun Zhang, Kathleen L. McCann, Chen Qiu, Lauren E. Gonzalez, Susan J. Baserga, Traci M. Tanaka Hall |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2016
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Materias: | |
Acceso en línea: | https://doaj.org/article/faa28510bd764afbbb1cc91b25bbfcb8 |
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