Locoregional Therapies for Hepatocellular Carcinoma with Portal Vein Tumor Thrombosis

Hepatocellular carcinoma is the fourth leading cause of cancer worldwide, and the fastest increasing cause of cancer mortality in the United States. Its propensity for vascular invasion leads to the presence of portal vein tumor thrombus in up to half of patients. PVTT results in a classification of...

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Autores principales:	Kylie E. Zane, Mina S. Makary
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	HCC portal vein tumor thrombus TACE SIRT ablation TARE Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Acceso en línea:	https://doaj.org/article/fab686aa90c24823b4c7e8aeb065a815
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spelling	oai:doaj.org-article:fab686aa90c24823b4c7e8aeb065a8152021-11-11T15:31:24ZLocoregional Therapies for Hepatocellular Carcinoma with Portal Vein Tumor Thrombosis10.3390/cancers132154302072-6694https://doaj.org/article/fab686aa90c24823b4c7e8aeb065a8152021-10-01T00:00:00Zhttps://www.mdpi.com/2072-6694/13/21/5430https://doaj.org/toc/2072-6694Hepatocellular carcinoma is the fourth leading cause of cancer worldwide, and the fastest increasing cause of cancer mortality in the United States. Its propensity for vascular invasion leads to the presence of portal vein tumor thrombus in up to half of patients. PVTT results in a classification of advanced disease, given the risk recurrence secondary to intravascular spread, and formal guidelines recommend systemic therapy in these patients. However, recent advances in locoregional therapies including TACE, TARE, and ablation have demonstrated the potential to drastically improve overall survival in patients with HCC complicated by PVTT.Kylie E. ZaneMina S. MakaryMDPI AGarticleHCCportal vein tumor thrombusTACESIRTablationTARENeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENCancers, Vol 13, Iss 5430, p 5430 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	HCC portal vein tumor thrombus TACE SIRT ablation TARE Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
spellingShingle	HCC portal vein tumor thrombus TACE SIRT ablation TARE Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Kylie E. Zane Mina S. Makary Locoregional Therapies for Hepatocellular Carcinoma with Portal Vein Tumor Thrombosis
description	Hepatocellular carcinoma is the fourth leading cause of cancer worldwide, and the fastest increasing cause of cancer mortality in the United States. Its propensity for vascular invasion leads to the presence of portal vein tumor thrombus in up to half of patients. PVTT results in a classification of advanced disease, given the risk recurrence secondary to intravascular spread, and formal guidelines recommend systemic therapy in these patients. However, recent advances in locoregional therapies including TACE, TARE, and ablation have demonstrated the potential to drastically improve overall survival in patients with HCC complicated by PVTT.
format	article
author	Kylie E. Zane Mina S. Makary
author_facet	Kylie E. Zane Mina S. Makary
author_sort	Kylie E. Zane
title	Locoregional Therapies for Hepatocellular Carcinoma with Portal Vein Tumor Thrombosis
title_short	Locoregional Therapies for Hepatocellular Carcinoma with Portal Vein Tumor Thrombosis
title_full	Locoregional Therapies for Hepatocellular Carcinoma with Portal Vein Tumor Thrombosis
title_fullStr	Locoregional Therapies for Hepatocellular Carcinoma with Portal Vein Tumor Thrombosis
title_full_unstemmed	Locoregional Therapies for Hepatocellular Carcinoma with Portal Vein Tumor Thrombosis
title_sort	locoregional therapies for hepatocellular carcinoma with portal vein tumor thrombosis
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/fab686aa90c24823b4c7e8aeb065a815
work_keys_str_mv	AT kylieezane locoregionaltherapiesforhepatocellularcarcinomawithportalveintumorthrombosis AT minasmakary locoregionaltherapiesforhepatocellularcarcinomawithportalveintumorthrombosis
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Locoregional Therapies for Hepatocellular Carcinoma with Portal Vein Tumor Thrombosis

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