LYMPHOCYTE APOPTOSIS AND PROLIFERATIVE ACTIVITY IN PATIENTS WITH PULMONARY TUBERCULOSIS AND MULTIPLE DRUG RESISTANCE OF M. TUBERCULOSIS

Abstract. The work concerned some parameters of proliferation and apoptosis in peripheral blood lymphocytes in patients with primary pulmonary tuberculosis (Tbc), as dependent on clinical form of the disease and sensitivity of M. tuberculosis to specific medical drugs. It was shown that, in patients...

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Autores principales:	E. G. Churina, V. V. Novitsky, O. I. Urazova, O. V. Filinyuk, N. V. Teplova, I. E. Esimova
Formato:	article
Lenguaje:	RU
Publicado:	SPb RAACI 2014
Materias:	lung tuberculosis drug resistance lymphocytes proliferation apoptosis Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/fac6c96d7b4e42f9bae4176e431a84c3
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spelling	oai:doaj.org-article:fac6c96d7b4e42f9bae4176e431a84c32021-11-18T08:03:40ZLYMPHOCYTE APOPTOSIS AND PROLIFERATIVE ACTIVITY IN PATIENTS WITH PULMONARY TUBERCULOSIS AND MULTIPLE DRUG RESISTANCE OF M. TUBERCULOSIS1563-06252313-741X10.15789/1563-0625-2012-1-2-119-126https://doaj.org/article/fac6c96d7b4e42f9bae4176e431a84c32014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/307https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAbstract. The work concerned some parameters of proliferation and apoptosis in peripheral blood lymphocytes in patients with primary pulmonary tuberculosis (Tbc), as dependent on clinical form of the disease and sensitivity of M. tuberculosis to specific medical drugs. It was shown that, in patients with infiltrative and disseminated Tbc, as well as in cases of multi-drug resistance of M. tuberculosis, an increased apoptosis of lymphocytes is observed, accompanied by inhibition of their proliferative activity. The numbers of apoptotic and proliferating lymphocytes remain within normal ranges in patients with fibrous/cavernous form of the disease, and in cases of drug-sensitive M. tuberculosis.E. G. ChurinaV. V. NovitskyO. I. UrazovaO. V. FilinyukN. V. TeplovaI. E. EsimovaSPb RAACIarticlelung tuberculosisdrug resistancelymphocytesproliferationapoptosisImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 14, Iss 1-2, Pp 119-126 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	lung tuberculosis drug resistance lymphocytes proliferation apoptosis Immunologic diseases. Allergy RC581-607
spellingShingle	lung tuberculosis drug resistance lymphocytes proliferation apoptosis Immunologic diseases. Allergy RC581-607 E. G. Churina V. V. Novitsky O. I. Urazova O. V. Filinyuk N. V. Teplova I. E. Esimova LYMPHOCYTE APOPTOSIS AND PROLIFERATIVE ACTIVITY IN PATIENTS WITH PULMONARY TUBERCULOSIS AND MULTIPLE DRUG RESISTANCE OF M. TUBERCULOSIS
description	Abstract. The work concerned some parameters of proliferation and apoptosis in peripheral blood lymphocytes in patients with primary pulmonary tuberculosis (Tbc), as dependent on clinical form of the disease and sensitivity of M. tuberculosis to specific medical drugs. It was shown that, in patients with infiltrative and disseminated Tbc, as well as in cases of multi-drug resistance of M. tuberculosis, an increased apoptosis of lymphocytes is observed, accompanied by inhibition of their proliferative activity. The numbers of apoptotic and proliferating lymphocytes remain within normal ranges in patients with fibrous/cavernous form of the disease, and in cases of drug-sensitive M. tuberculosis.
format	article
author	E. G. Churina V. V. Novitsky O. I. Urazova O. V. Filinyuk N. V. Teplova I. E. Esimova
author_facet	E. G. Churina V. V. Novitsky O. I. Urazova O. V. Filinyuk N. V. Teplova I. E. Esimova
author_sort	E. G. Churina
title	LYMPHOCYTE APOPTOSIS AND PROLIFERATIVE ACTIVITY IN PATIENTS WITH PULMONARY TUBERCULOSIS AND MULTIPLE DRUG RESISTANCE OF M. TUBERCULOSIS
title_short	LYMPHOCYTE APOPTOSIS AND PROLIFERATIVE ACTIVITY IN PATIENTS WITH PULMONARY TUBERCULOSIS AND MULTIPLE DRUG RESISTANCE OF M. TUBERCULOSIS
title_full	LYMPHOCYTE APOPTOSIS AND PROLIFERATIVE ACTIVITY IN PATIENTS WITH PULMONARY TUBERCULOSIS AND MULTIPLE DRUG RESISTANCE OF M. TUBERCULOSIS
title_fullStr	LYMPHOCYTE APOPTOSIS AND PROLIFERATIVE ACTIVITY IN PATIENTS WITH PULMONARY TUBERCULOSIS AND MULTIPLE DRUG RESISTANCE OF M. TUBERCULOSIS
title_full_unstemmed	LYMPHOCYTE APOPTOSIS AND PROLIFERATIVE ACTIVITY IN PATIENTS WITH PULMONARY TUBERCULOSIS AND MULTIPLE DRUG RESISTANCE OF M. TUBERCULOSIS
title_sort	lymphocyte apoptosis and proliferative activity in patients with pulmonary tuberculosis and multiple drug resistance of m. tuberculosis
publisher	SPb RAACI
publishDate	2014
url	https://doaj.org/article/fac6c96d7b4e42f9bae4176e431a84c3
work_keys_str_mv	AT egchurina lymphocyteapoptosisandproliferativeactivityinpatientswithpulmonarytuberculosisandmultipledrugresistanceofmtuberculosis AT vvnovitsky lymphocyteapoptosisandproliferativeactivityinpatientswithpulmonarytuberculosisandmultipledrugresistanceofmtuberculosis AT oiurazova lymphocyteapoptosisandproliferativeactivityinpatientswithpulmonarytuberculosisandmultipledrugresistanceofmtuberculosis AT ovfilinyuk lymphocyteapoptosisandproliferativeactivityinpatientswithpulmonarytuberculosisandmultipledrugresistanceofmtuberculosis AT nvteplova lymphocyteapoptosisandproliferativeactivityinpatientswithpulmonarytuberculosisandmultipledrugresistanceofmtuberculosis AT ieesimova lymphocyteapoptosisandproliferativeactivityinpatientswithpulmonarytuberculosisandmultipledrugresistanceofmtuberculosis
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LYMPHOCYTE APOPTOSIS AND PROLIFERATIVE ACTIVITY IN PATIENTS WITH PULMONARY TUBERCULOSIS AND MULTIPLE DRUG RESISTANCE OF M. TUBERCULOSIS

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