The fluorination effect of fluoroamphiphiles in cytosolic protein delivery

Proteins can serve as means of medical treatment, but their efficient delivery to cells is difficult. Here, the authors present a type of polymers, fluoroamphiphiles, acting as chemical chaperones that can facilitate the import of proteins into the inner compartment, i.e. cytosol, of cells.

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Autores principales:	Zhenjing Zhang, Wanwan Shen, Jing Ling, Yang Yan, Jingjing Hu, Yiyun Cheng
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/fad39cd185194ad39cc2d484c2bd4eb0
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spelling	oai:doaj.org-article:fad39cd185194ad39cc2d484c2bd4eb02021-12-02T14:41:16ZThe fluorination effect of fluoroamphiphiles in cytosolic protein delivery10.1038/s41467-018-03779-82041-1723https://doaj.org/article/fad39cd185194ad39cc2d484c2bd4eb02018-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03779-8https://doaj.org/toc/2041-1723Proteins can serve as means of medical treatment, but their efficient delivery to cells is difficult. Here, the authors present a type of polymers, fluoroamphiphiles, acting as chemical chaperones that can facilitate the import of proteins into the inner compartment, i.e. cytosol, of cells.Zhenjing ZhangWanwan ShenJing LingYang YanJingjing HuYiyun ChengNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Zhenjing Zhang Wanwan Shen Jing Ling Yang Yan Jingjing Hu Yiyun Cheng The fluorination effect of fluoroamphiphiles in cytosolic protein delivery
description	Proteins can serve as means of medical treatment, but their efficient delivery to cells is difficult. Here, the authors present a type of polymers, fluoroamphiphiles, acting as chemical chaperones that can facilitate the import of proteins into the inner compartment, i.e. cytosol, of cells.
format	article
author	Zhenjing Zhang Wanwan Shen Jing Ling Yang Yan Jingjing Hu Yiyun Cheng
author_facet	Zhenjing Zhang Wanwan Shen Jing Ling Yang Yan Jingjing Hu Yiyun Cheng
author_sort	Zhenjing Zhang
title	The fluorination effect of fluoroamphiphiles in cytosolic protein delivery
title_short	The fluorination effect of fluoroamphiphiles in cytosolic protein delivery
title_full	The fluorination effect of fluoroamphiphiles in cytosolic protein delivery
title_fullStr	The fluorination effect of fluoroamphiphiles in cytosolic protein delivery
title_full_unstemmed	The fluorination effect of fluoroamphiphiles in cytosolic protein delivery
title_sort	fluorination effect of fluoroamphiphiles in cytosolic protein delivery
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/fad39cd185194ad39cc2d484c2bd4eb0
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The fluorination effect of fluoroamphiphiles in cytosolic protein delivery

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