Administration of supplemental L-tyrosine with phenelzine: a clinical literature review

Marty Hinz,1 Alvin Stein,2 Ted Cole,3 Patricia Ryan4 1Clinical Research, NeuroResearch Clinics, Inc., Cape Coral, FL, USA; 2Stein Orthopedic Associates, Plantation, FL, USA; 3Cole Center for Healing, Cincinnati, OH, USA; 4Family Wellness Center, Omaha, NE, USA Abstract: The subject of this literat...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Hinz M, Stein A, Cole T, Ryan P
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2014
Materias:	Therapeutics. Pharmacology RM1-950
Acceso en línea:	https://doaj.org/article/fadbb78b0c0846329256583d2e29c405
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:fadbb78b0c0846329256583d2e29c405
record_format	dspace
spelling	oai:doaj.org-article:fadbb78b0c0846329256583d2e29c4052021-12-02T06:17:29ZAdministration of supplemental L-tyrosine with phenelzine: a clinical literature review1179-1438https://doaj.org/article/fadbb78b0c0846329256583d2e29c4052014-07-01T00:00:00Zhttp://www.dovepress.com/administration-of-supplemental-l-tyrosine-with-phenelzine-a-clinical-l-peer-reviewed-article-CPAAhttps://doaj.org/toc/1179-1438 Marty Hinz,1 Alvin Stein,2 Ted Cole,3 Patricia Ryan4 1Clinical Research, NeuroResearch Clinics, Inc., Cape Coral, FL, USA; 2Stein Orthopedic Associates, Plantation, FL, USA; 3Cole Center for Healing, Cincinnati, OH, USA; 4Family Wellness Center, Omaha, NE, USA Abstract: The subject of this literature review is the alleged relationship between L-tyrosine, phenelzine, and hypertensive crisis. Phenelzine (Nardil®) prescribing information notes: “The potentiation of sympathomimetic substances and related compounds by MAO inhibitors may result in hypertensive crises (see WARNINGS). Therefore, patients being treated with NARDIL should not take […] L-tyrosine […]”. Interest in the scientific foundation of this claim was generated during routine patient care. A comprehensive literature search of Google Scholar and PubMed revealed no reported cases of hypertensive crisis associated with concomitant administration of L-tyrosine and phenelzine. Review of current US Food and Drug Administration nutritional guidelines relating to ongoing phenelzine studies reveals no mention and requires no consideration of L-tyrosine ingestion in combination with phenelzine. This paper is intended to provide an objective review of the science to then allow the reader to formulate the final opinion. Keywords: hypertensive crisis, phenelzine, tyrosine, tyramine, stroke, phenelzineHinz MStein ACole TRyan PDove Medical PressarticleTherapeutics. PharmacologyRM1-950ENClinical Pharmacology: Advances and Applications, Vol 2014, Iss default, Pp 107-110 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Therapeutics. Pharmacology RM1-950
spellingShingle	Therapeutics. Pharmacology RM1-950 Hinz M Stein A Cole T Ryan P Administration of supplemental L-tyrosine with phenelzine: a clinical literature review
description	Marty Hinz,1 Alvin Stein,2 Ted Cole,3 Patricia Ryan4 1Clinical Research, NeuroResearch Clinics, Inc., Cape Coral, FL, USA; 2Stein Orthopedic Associates, Plantation, FL, USA; 3Cole Center for Healing, Cincinnati, OH, USA; 4Family Wellness Center, Omaha, NE, USA Abstract: The subject of this literature review is the alleged relationship between L-tyrosine, phenelzine, and hypertensive crisis. Phenelzine (Nardil®) prescribing information notes: “The potentiation of sympathomimetic substances and related compounds by MAO inhibitors may result in hypertensive crises (see WARNINGS). Therefore, patients being treated with NARDIL should not take […] L-tyrosine […]”. Interest in the scientific foundation of this claim was generated during routine patient care. A comprehensive literature search of Google Scholar and PubMed revealed no reported cases of hypertensive crisis associated with concomitant administration of L-tyrosine and phenelzine. Review of current US Food and Drug Administration nutritional guidelines relating to ongoing phenelzine studies reveals no mention and requires no consideration of L-tyrosine ingestion in combination with phenelzine. This paper is intended to provide an objective review of the science to then allow the reader to formulate the final opinion. Keywords: hypertensive crisis, phenelzine, tyrosine, tyramine, stroke, phenelzine
format	article
author	Hinz M Stein A Cole T Ryan P
author_facet	Hinz M Stein A Cole T Ryan P
author_sort	Hinz M
title	Administration of supplemental L-tyrosine with phenelzine: a clinical literature review
title_short	Administration of supplemental L-tyrosine with phenelzine: a clinical literature review
title_full	Administration of supplemental L-tyrosine with phenelzine: a clinical literature review
title_fullStr	Administration of supplemental L-tyrosine with phenelzine: a clinical literature review
title_full_unstemmed	Administration of supplemental L-tyrosine with phenelzine: a clinical literature review
title_sort	administration of supplemental l-tyrosine with phenelzine: a clinical literature review
publisher	Dove Medical Press
publishDate	2014
url	https://doaj.org/article/fadbb78b0c0846329256583d2e29c405
work_keys_str_mv	AT hinzm administrationofsupplementalltyrosinewithphenelzineaclinicalliteraturereview AT steina administrationofsupplementalltyrosinewithphenelzineaclinicalliteraturereview AT colet administrationofsupplementalltyrosinewithphenelzineaclinicalliteraturereview AT ryanp administrationofsupplementalltyrosinewithphenelzineaclinicalliteraturereview
_version_	1718400030945050624

Administration of supplemental L-tyrosine with phenelzine: a clinical literature review

Ejemplares similares