Capsid protein structure in Zika virus reveals the flavivirus assembly process

The structure of flavivirus surface proteins has been elucidated, but the conformation of capsid proteins within particles is less clear. Here, the authors provide a subnanometer resolution structure of Zika virus capsid protein within the virus particle, elucidating its quaternary organization and...

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Autores principales: Ter Yong Tan, Guntur Fibriansah, Victor A. Kostyuchenko, Thiam-Seng Ng, Xin-Xiang Lim, Shuijun Zhang, Xin-Ni Lim, Jiaqi Wang, Jian Shi, Marc C. Morais, Davide Corti, Shee-Mei Lok
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/fae32c41b76f496b9784d9e9a446761f
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Sumario:The structure of flavivirus surface proteins has been elucidated, but the conformation of capsid proteins within particles is less clear. Here, the authors provide a subnanometer resolution structure of Zika virus capsid protein within the virus particle, elucidating its quaternary organization and role in flavivirus packaging.