Capsid protein structure in Zika virus reveals the flavivirus assembly process

The structure of flavivirus surface proteins has been elucidated, but the conformation of capsid proteins within particles is less clear. Here, the authors provide a subnanometer resolution structure of Zika virus capsid protein within the virus particle, elucidating its quaternary organization and...

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Autores principales: Ter Yong Tan, Guntur Fibriansah, Victor A. Kostyuchenko, Thiam-Seng Ng, Xin-Xiang Lim, Shuijun Zhang, Xin-Ni Lim, Jiaqi Wang, Jian Shi, Marc C. Morais, Davide Corti, Shee-Mei Lok
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/fae32c41b76f496b9784d9e9a446761f
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spelling oai:doaj.org-article:fae32c41b76f496b9784d9e9a446761f2021-12-02T14:41:26ZCapsid protein structure in Zika virus reveals the flavivirus assembly process10.1038/s41467-020-14647-92041-1723https://doaj.org/article/fae32c41b76f496b9784d9e9a446761f2020-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14647-9https://doaj.org/toc/2041-1723The structure of flavivirus surface proteins has been elucidated, but the conformation of capsid proteins within particles is less clear. Here, the authors provide a subnanometer resolution structure of Zika virus capsid protein within the virus particle, elucidating its quaternary organization and role in flavivirus packaging.Ter Yong TanGuntur FibriansahVictor A. KostyuchenkoThiam-Seng NgXin-Xiang LimShuijun ZhangXin-Ni LimJiaqi WangJian ShiMarc C. MoraisDavide CortiShee-Mei LokNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Ter Yong Tan
Guntur Fibriansah
Victor A. Kostyuchenko
Thiam-Seng Ng
Xin-Xiang Lim
Shuijun Zhang
Xin-Ni Lim
Jiaqi Wang
Jian Shi
Marc C. Morais
Davide Corti
Shee-Mei Lok
Capsid protein structure in Zika virus reveals the flavivirus assembly process
description The structure of flavivirus surface proteins has been elucidated, but the conformation of capsid proteins within particles is less clear. Here, the authors provide a subnanometer resolution structure of Zika virus capsid protein within the virus particle, elucidating its quaternary organization and role in flavivirus packaging.
format article
author Ter Yong Tan
Guntur Fibriansah
Victor A. Kostyuchenko
Thiam-Seng Ng
Xin-Xiang Lim
Shuijun Zhang
Xin-Ni Lim
Jiaqi Wang
Jian Shi
Marc C. Morais
Davide Corti
Shee-Mei Lok
author_facet Ter Yong Tan
Guntur Fibriansah
Victor A. Kostyuchenko
Thiam-Seng Ng
Xin-Xiang Lim
Shuijun Zhang
Xin-Ni Lim
Jiaqi Wang
Jian Shi
Marc C. Morais
Davide Corti
Shee-Mei Lok
author_sort Ter Yong Tan
title Capsid protein structure in Zika virus reveals the flavivirus assembly process
title_short Capsid protein structure in Zika virus reveals the flavivirus assembly process
title_full Capsid protein structure in Zika virus reveals the flavivirus assembly process
title_fullStr Capsid protein structure in Zika virus reveals the flavivirus assembly process
title_full_unstemmed Capsid protein structure in Zika virus reveals the flavivirus assembly process
title_sort capsid protein structure in zika virus reveals the flavivirus assembly process
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/fae32c41b76f496b9784d9e9a446761f
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