Biogenic manganese oxide nanoparticle formation by a multimeric multicopper oxidase Mnx

Significant challenges exist for structural characterization of enzymes responsible for biomineralization. Here the authors show that native mass spectrometry and high resolution electron microscopy can define the subunit topology and copper binding of a manganese oxidizing complex, and describe ear...

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Autores principales: Christine A. Romano, Mowei Zhou, Yang Song, Vicki H. Wysocki, Alice C. Dohnalkova, Libor Kovarik, Ljiljana Paša-Tolić, Bradley M. Tebo
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/fae55337cabe456889f445376dc0e79e
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Sumario:Significant challenges exist for structural characterization of enzymes responsible for biomineralization. Here the authors show that native mass spectrometry and high resolution electron microscopy can define the subunit topology and copper binding of a manganese oxidizing complex, and describe early stage formation of its mineral products