The Role of RNA Methylation in Regulating Stem Cell Fate and Function-Focus on m6A
The biological role of RNA methylation in stem cells has attracted increasing attention. Recent studies have demonstrated that RNA methylation plays a crucial role in self-renewal, differentiation, and tumorigenicity of stem cells. In this review, we focus on the biological role of RNA methylation m...
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Hindawi Limited
2021
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oai:doaj.org-article:faedafc3376a4d5c8b5769aa953502582021-11-08T02:35:37ZThe Role of RNA Methylation in Regulating Stem Cell Fate and Function-Focus on m6A1687-967810.1155/2021/8874360https://doaj.org/article/faedafc3376a4d5c8b5769aa953502582021-01-01T00:00:00Zhttp://dx.doi.org/10.1155/2021/8874360https://doaj.org/toc/1687-9678The biological role of RNA methylation in stem cells has attracted increasing attention. Recent studies have demonstrated that RNA methylation plays a crucial role in self-renewal, differentiation, and tumorigenicity of stem cells. In this review, we focus on the biological role of RNA methylation modifications including N6-methyladenosine, 5-methylcytosine, and uridylation in embryonic stem cells, adult stem cells, induced pluripotent stem cells, and cancer stem cells, so as to provide new insights into the potential innovative treatments of cancer or other complex diseases.Weiwei SunBin ZhangQingli BieNa MaNa LiuZewei ShaoHindawi LimitedarticleInternal medicineRC31-1245ENStem Cells International, Vol 2021 (2021) |
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DOAJ |
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DOAJ |
| language |
EN |
| topic |
Internal medicine RC31-1245 |
| spellingShingle |
Internal medicine RC31-1245 Weiwei Sun Bin Zhang Qingli Bie Na Ma Na Liu Zewei Shao The Role of RNA Methylation in Regulating Stem Cell Fate and Function-Focus on m6A |
| description |
The biological role of RNA methylation in stem cells has attracted increasing attention. Recent studies have demonstrated that RNA methylation plays a crucial role in self-renewal, differentiation, and tumorigenicity of stem cells. In this review, we focus on the biological role of RNA methylation modifications including N6-methyladenosine, 5-methylcytosine, and uridylation in embryonic stem cells, adult stem cells, induced pluripotent stem cells, and cancer stem cells, so as to provide new insights into the potential innovative treatments of cancer or other complex diseases. |
| format |
article |
| author |
Weiwei Sun Bin Zhang Qingli Bie Na Ma Na Liu Zewei Shao |
| author_facet |
Weiwei Sun Bin Zhang Qingli Bie Na Ma Na Liu Zewei Shao |
| author_sort |
Weiwei Sun |
| title |
The Role of RNA Methylation in Regulating Stem Cell Fate and Function-Focus on m6A |
| title_short |
The Role of RNA Methylation in Regulating Stem Cell Fate and Function-Focus on m6A |
| title_full |
The Role of RNA Methylation in Regulating Stem Cell Fate and Function-Focus on m6A |
| title_fullStr |
The Role of RNA Methylation in Regulating Stem Cell Fate and Function-Focus on m6A |
| title_full_unstemmed |
The Role of RNA Methylation in Regulating Stem Cell Fate and Function-Focus on m6A |
| title_sort |
role of rna methylation in regulating stem cell fate and function-focus on m6a |
| publisher |
Hindawi Limited |
| publishDate |
2021 |
| url |
https://doaj.org/article/faedafc3376a4d5c8b5769aa95350258 |
| work_keys_str_mv |
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