De novo emergence of adaptive membrane proteins from thymine-rich genomic sequences

There is increasing evidence that protein-coding genes can emerge de novo from noncoding genomic regions. Vakirlis et al. propose that sequences encoding transmembrane polypeptides can emerge de novo in thymine-rich genomic regions and provide organisms with fitness benefits.

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Autores principales:	Nikolaos Vakirlis, Omer Acar, Brian Hsu, Nelson Castilho Coelho, S. Branden Van Oss, Aaron Wacholder, Kate Medetgul-Ernar, Ray W. Bowman, Cameron P. Hines, John Iannotta, Saurin Bipin Parikh, Aoife McLysaght, Carlos J. Camacho, Allyson F. O’Donnell, Trey Ideker, Anne-Ruxandra Carvunis
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/faf179aee3974a3a939a01b1132508f8
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spelling	oai:doaj.org-article:faf179aee3974a3a939a01b1132508f82021-12-02T15:39:10ZDe novo emergence of adaptive membrane proteins from thymine-rich genomic sequences10.1038/s41467-020-14500-z2041-1723https://doaj.org/article/faf179aee3974a3a939a01b1132508f82020-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14500-zhttps://doaj.org/toc/2041-1723There is increasing evidence that protein-coding genes can emerge de novo from noncoding genomic regions. Vakirlis et al. propose that sequences encoding transmembrane polypeptides can emerge de novo in thymine-rich genomic regions and provide organisms with fitness benefits.Nikolaos VakirlisOmer AcarBrian HsuNelson Castilho CoelhoS. Branden Van OssAaron WacholderKate Medetgul-ErnarRay W. BowmanCameron P. HinesJohn IannottaSaurin Bipin ParikhAoife McLysaghtCarlos J. CamachoAllyson F. O’DonnellTrey IdekerAnne-Ruxandra CarvunisNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Nikolaos Vakirlis Omer Acar Brian Hsu Nelson Castilho Coelho S. Branden Van Oss Aaron Wacholder Kate Medetgul-Ernar Ray W. Bowman Cameron P. Hines John Iannotta Saurin Bipin Parikh Aoife McLysaght Carlos J. Camacho Allyson F. O’Donnell Trey Ideker Anne-Ruxandra Carvunis De novo emergence of adaptive membrane proteins from thymine-rich genomic sequences
description	There is increasing evidence that protein-coding genes can emerge de novo from noncoding genomic regions. Vakirlis et al. propose that sequences encoding transmembrane polypeptides can emerge de novo in thymine-rich genomic regions and provide organisms with fitness benefits.
format	article
author	Nikolaos Vakirlis Omer Acar Brian Hsu Nelson Castilho Coelho S. Branden Van Oss Aaron Wacholder Kate Medetgul-Ernar Ray W. Bowman Cameron P. Hines John Iannotta Saurin Bipin Parikh Aoife McLysaght Carlos J. Camacho Allyson F. O’Donnell Trey Ideker Anne-Ruxandra Carvunis
author_facet	Nikolaos Vakirlis Omer Acar Brian Hsu Nelson Castilho Coelho S. Branden Van Oss Aaron Wacholder Kate Medetgul-Ernar Ray W. Bowman Cameron P. Hines John Iannotta Saurin Bipin Parikh Aoife McLysaght Carlos J. Camacho Allyson F. O’Donnell Trey Ideker Anne-Ruxandra Carvunis
author_sort	Nikolaos Vakirlis
title	De novo emergence of adaptive membrane proteins from thymine-rich genomic sequences
title_short	De novo emergence of adaptive membrane proteins from thymine-rich genomic sequences
title_full	De novo emergence of adaptive membrane proteins from thymine-rich genomic sequences
title_fullStr	De novo emergence of adaptive membrane proteins from thymine-rich genomic sequences
title_full_unstemmed	De novo emergence of adaptive membrane proteins from thymine-rich genomic sequences
title_sort	de novo emergence of adaptive membrane proteins from thymine-rich genomic sequences
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/faf179aee3974a3a939a01b1132508f8
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De novo emergence of adaptive membrane proteins from thymine-rich genomic sequences

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