Enhancing Cancer Immunotherapy Treatment Goals by Using Nanoparticle Delivery System

Tobias Achu Muluh,1,* Zhuo Chen,1,* Yi Li,1,* Kang Xiong,1 Jing Jin,1 ShaoZhi Fu,1– 3 JingBo Wu1– 3 1Department of Oncology, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, Sichuan, People’s Republic of China; 2Nuclear Medicine and Molecular Ima...

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Autores principales:	Muluh TA, Chen Z, Li Y, Xiong K, Jin J, Fu S, Wu J
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2021
Materias:	tumor immunotherapy immune system nanoparticles drug delivery drug release. Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/fb091bb50d57426d9779bd86300f47d9
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spelling	oai:doaj.org-article:fb091bb50d57426d9779bd86300f47d92021-12-02T14:17:59ZEnhancing Cancer Immunotherapy Treatment Goals by Using Nanoparticle Delivery System1178-2013https://doaj.org/article/fb091bb50d57426d9779bd86300f47d92021-03-01T00:00:00Zhttps://www.dovepress.com/enhancing-cancer-immunotherapy-treatment-goals-by-using-nanoparticle-d-peer-reviewed-article-IJNhttps://doaj.org/toc/1178-2013Tobias Achu Muluh,1,* Zhuo Chen,1,* Yi Li,1,* Kang Xiong,1 Jing Jin,1 ShaoZhi Fu,1– 3 JingBo Wu1– 3 1Department of Oncology, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, Sichuan, People’s Republic of China; 2Nuclear Medicine and Molecular Imaging Key Laboratory of Sichuan Province, Luzhou, 646000, Sichuan, People’s Republic of China; 3Department of Oncology, Academician (Expert) Workstation of Sichuan Province, Luzhou, Sichuan, 646000, People’s Republic of China*These authors contributed equally to this workCorrespondence: ShaoZhi Fu; JingBo WuDepartment of Oncology, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, Sichuan, People’s Republic of ChinaTel/Fax +86 8303165696Email shaozhifu513@163.com; wjb6147@163.comAbstract: Recently, there has been an incredible increase in research about the abnormal growth of cells (neoplasm), focusing on the management, treatment and preventing reoccurrence. It has been understood that the natural defense system, composed of a variety of immune defensive cells, does not just limit its function in eliminating neoplastic cells, but also controls the growth and spread of tumor cells of different kinds to other parts of the body. Cancer immunotherapy, is a cancer treatment plan that educates the body’s defensive system to forestall, control, and eliminate tumor cells. The effectiveness of immunotherapy is achieved, to its highest efficacy, by the use of nanoparticles (NPs) for precise and timely delivery of immunotherapies to specific targeted neoplasms, with less or no harm to the healthy cells. Immunotherapies have been affirmed in clinical trials as a cancer regimen for various types of cancers, the side effects resulting from imprecise and non-targeted conveyance is well managed with the use of nanoparticles. Nonetheless, we will concentrate on enhancing cancer immunotherapy approaches by the use of nanoparticles for the productivity of antitumor immunity. Nanoparticles will be presented and utilized as an objective immunotherapy delivery system for high exactness and are thus a promising methodology for cancer treatment.Keywords: tumor immunotherapy, immune system, nanoparticles, drug delivery, drug releaseMuluh TAChen ZLi YXiong KJin JFu SWu JDove Medical Pressarticletumor immunotherapyimmune systemnanoparticlesdrug deliverydrug release.Medicine (General)R5-920ENInternational Journal of Nanomedicine, Vol Volume 16, Pp 2389-2404 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	tumor immunotherapy immune system nanoparticles drug delivery drug release. Medicine (General) R5-920
spellingShingle	tumor immunotherapy immune system nanoparticles drug delivery drug release. Medicine (General) R5-920 Muluh TA Chen Z Li Y Xiong K Jin J Fu S Wu J Enhancing Cancer Immunotherapy Treatment Goals by Using Nanoparticle Delivery System
description	Tobias Achu Muluh,1,* Zhuo Chen,1,* Yi Li,1,* Kang Xiong,1 Jing Jin,1 ShaoZhi Fu,1– 3 JingBo Wu1– 3 1Department of Oncology, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, Sichuan, People’s Republic of China; 2Nuclear Medicine and Molecular Imaging Key Laboratory of Sichuan Province, Luzhou, 646000, Sichuan, People’s Republic of China; 3Department of Oncology, Academician (Expert) Workstation of Sichuan Province, Luzhou, Sichuan, 646000, People’s Republic of China*These authors contributed equally to this workCorrespondence: ShaoZhi Fu; JingBo WuDepartment of Oncology, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, Sichuan, People’s Republic of ChinaTel/Fax +86 8303165696Email shaozhifu513@163.com; wjb6147@163.comAbstract: Recently, there has been an incredible increase in research about the abnormal growth of cells (neoplasm), focusing on the management, treatment and preventing reoccurrence. It has been understood that the natural defense system, composed of a variety of immune defensive cells, does not just limit its function in eliminating neoplastic cells, but also controls the growth and spread of tumor cells of different kinds to other parts of the body. Cancer immunotherapy, is a cancer treatment plan that educates the body’s defensive system to forestall, control, and eliminate tumor cells. The effectiveness of immunotherapy is achieved, to its highest efficacy, by the use of nanoparticles (NPs) for precise and timely delivery of immunotherapies to specific targeted neoplasms, with less or no harm to the healthy cells. Immunotherapies have been affirmed in clinical trials as a cancer regimen for various types of cancers, the side effects resulting from imprecise and non-targeted conveyance is well managed with the use of nanoparticles. Nonetheless, we will concentrate on enhancing cancer immunotherapy approaches by the use of nanoparticles for the productivity of antitumor immunity. Nanoparticles will be presented and utilized as an objective immunotherapy delivery system for high exactness and are thus a promising methodology for cancer treatment.Keywords: tumor immunotherapy, immune system, nanoparticles, drug delivery, drug release
format	article
author	Muluh TA Chen Z Li Y Xiong K Jin J Fu S Wu J
author_facet	Muluh TA Chen Z Li Y Xiong K Jin J Fu S Wu J
author_sort	Muluh TA
title	Enhancing Cancer Immunotherapy Treatment Goals by Using Nanoparticle Delivery System
title_short	Enhancing Cancer Immunotherapy Treatment Goals by Using Nanoparticle Delivery System
title_full	Enhancing Cancer Immunotherapy Treatment Goals by Using Nanoparticle Delivery System
title_fullStr	Enhancing Cancer Immunotherapy Treatment Goals by Using Nanoparticle Delivery System
title_full_unstemmed	Enhancing Cancer Immunotherapy Treatment Goals by Using Nanoparticle Delivery System
title_sort	enhancing cancer immunotherapy treatment goals by using nanoparticle delivery system
publisher	Dove Medical Press
publishDate	2021
url	https://doaj.org/article/fb091bb50d57426d9779bd86300f47d9
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Enhancing Cancer Immunotherapy Treatment Goals by Using Nanoparticle Delivery System

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