Cerebrospinal fluid lipocalin 2 as a novel biomarker for the differential diagnosis of vascular dementia
Diagnosis of vascular dementia is hampered by the lack of biochemical markers for this disease. Here, the authors show that vascular dementia is associated with increased lipocalin-2 in cerebrospinal fluid, compared to controls and patients with other forms of dementia.
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Nature Portfolio
2020
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oai:doaj.org-article:fb0e9a75338a4a03b999da9efd91d3b82021-12-02T14:42:46ZCerebrospinal fluid lipocalin 2 as a novel biomarker for the differential diagnosis of vascular dementia10.1038/s41467-020-14373-22041-1723https://doaj.org/article/fb0e9a75338a4a03b999da9efd91d3b82020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14373-2https://doaj.org/toc/2041-1723Diagnosis of vascular dementia is hampered by the lack of biochemical markers for this disease. Here, the authors show that vascular dementia is associated with increased lipocalin-2 in cerebrospinal fluid, compared to controls and patients with other forms of dementia.Franc LlorensPeter HermannAnna Villar-PiquéDaniela Diaz-LucenaKatarina NäggaOskar HanssonIsabel SantanaMatthias SchmitzChristian SchmidtDaniela VargesStefan GoebelJulien DumurgierHenrik ZetterbergKaj BlennowClaire PaquetInês BaldeirasIsidro FerrerInga ZerrNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020) |
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DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Franc Llorens Peter Hermann Anna Villar-Piqué Daniela Diaz-Lucena Katarina Nägga Oskar Hansson Isabel Santana Matthias Schmitz Christian Schmidt Daniela Varges Stefan Goebel Julien Dumurgier Henrik Zetterberg Kaj Blennow Claire Paquet Inês Baldeiras Isidro Ferrer Inga Zerr Cerebrospinal fluid lipocalin 2 as a novel biomarker for the differential diagnosis of vascular dementia |
| description |
Diagnosis of vascular dementia is hampered by the lack of biochemical markers for this disease. Here, the authors show that vascular dementia is associated with increased lipocalin-2 in cerebrospinal fluid, compared to controls and patients with other forms of dementia. |
| format |
article |
| author |
Franc Llorens Peter Hermann Anna Villar-Piqué Daniela Diaz-Lucena Katarina Nägga Oskar Hansson Isabel Santana Matthias Schmitz Christian Schmidt Daniela Varges Stefan Goebel Julien Dumurgier Henrik Zetterberg Kaj Blennow Claire Paquet Inês Baldeiras Isidro Ferrer Inga Zerr |
| author_facet |
Franc Llorens Peter Hermann Anna Villar-Piqué Daniela Diaz-Lucena Katarina Nägga Oskar Hansson Isabel Santana Matthias Schmitz Christian Schmidt Daniela Varges Stefan Goebel Julien Dumurgier Henrik Zetterberg Kaj Blennow Claire Paquet Inês Baldeiras Isidro Ferrer Inga Zerr |
| author_sort |
Franc Llorens |
| title |
Cerebrospinal fluid lipocalin 2 as a novel biomarker for the differential diagnosis of vascular dementia |
| title_short |
Cerebrospinal fluid lipocalin 2 as a novel biomarker for the differential diagnosis of vascular dementia |
| title_full |
Cerebrospinal fluid lipocalin 2 as a novel biomarker for the differential diagnosis of vascular dementia |
| title_fullStr |
Cerebrospinal fluid lipocalin 2 as a novel biomarker for the differential diagnosis of vascular dementia |
| title_full_unstemmed |
Cerebrospinal fluid lipocalin 2 as a novel biomarker for the differential diagnosis of vascular dementia |
| title_sort |
cerebrospinal fluid lipocalin 2 as a novel biomarker for the differential diagnosis of vascular dementia |
| publisher |
Nature Portfolio |
| publishDate |
2020 |
| url |
https://doaj.org/article/fb0e9a75338a4a03b999da9efd91d3b8 |
| work_keys_str_mv |
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1718389608240119808 |