Differential Immunoexpression of BRAF/V600E, Senescence Markers, PTEN, and T-type Calcium Channels in Acquired Naevi According to their Histopathological and Dermoscopic Classification

Differential Immunoexpression of BRAF/V600E, Senescence Markers, PTEN, and T-type Calcium Channels in Acquired Naevi According to their Histopathological and Dermoscopic Classification

BRAF/V600E mutation and other cell growth/growth-control mechanisms are involved in naevogenesis and melanomagenesis. Immunoexpression of BRAF/V600E and other molecules (p16, phosphatase and tensin homologue (PTEN), Ki67, hTERT and Cav3.1 and 3.2 calcium channels) were investigated in 80 histopatho­...

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Main Authors: Sara Moreno, Oscar Maiques, Carla Barcelo, Marta Romero, Maria Santacana, Ignacio Gómez, Dolors Cuevas, Ana Velasco, Alvar Vea, Anna Macia, Ramon Boix, Joan Valls, Sonia Gatius, Carles Canti, Xavier Matias-Guiu, Xavier Soria, Rosa M. Marti
Format: article
Language:EN
Published: Society for Publication of Acta Dermato-Venereologica 2021
Subjects:
acquired melanocytic naevus
BRAF-V600E
senescence markers
PTEN
T-type calcium channels
Dermatology
RL1-803
Online Access:https://doaj.org/article/fb10f1cd9c824c5b98cd290cac95a850
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https://doaj.org/article/fb10f1cd9c824c5b98cd290cac95a850

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