Association of handgrip strength with hospitalization, cardiovascular events, and mortality in Japanese patients with type 2 diabetes

Abstract Handgrip strength is useful for the diagnosis of sarcopenia. We examined the associations of handgrip strength with all-cause mortality, cardiovascular events, and hospitalization in patients with type 2 diabetes. From April 2013 to December 2015, we conducted a retrospective cohort study t...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Hidetaka Hamasaki, Yu Kawashima, Hisayuki Katsuyama, Akahito Sako, Atsushi Goto, Hidekatsu Yanai
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/fb252b70002c4ac29cfed1cd525fe395
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:fb252b70002c4ac29cfed1cd525fe395
record_format	dspace
spelling	oai:doaj.org-article:fb252b70002c4ac29cfed1cd525fe3952021-12-02T16:07:46ZAssociation of handgrip strength with hospitalization, cardiovascular events, and mortality in Japanese patients with type 2 diabetes10.1038/s41598-017-07438-82045-2322https://doaj.org/article/fb252b70002c4ac29cfed1cd525fe3952017-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-07438-8https://doaj.org/toc/2045-2322Abstract Handgrip strength is useful for the diagnosis of sarcopenia. We examined the associations of handgrip strength with all-cause mortality, cardiovascular events, and hospitalization in patients with type 2 diabetes. From April 2013 to December 2015, we conducted a retrospective cohort study to examine patients with type 2 diabetes whose handgrip strength was measured at our hospital. All patients were followed up until May 2016. A total of 1,282 patients (63.8 ± 13.9 years) were enrolled and followed up for 2.36 ± 0.73 years. During the follow-up period, 20 patients (1.6%) died, 14 (1.1%) experienced cardiovascular events, and 556 (43.4%) were admitted to our hospital for any diseases. Multiple regression analyses revealed that handgrip strength was favorably associated with abdominal obesity and renal function. Moreover, Cox proportional hazard analyses with adjustment for potential confounding variables revealed that handgrip strength was significantly associated with occurrence of CVD events and hospitalization in all subjects. In addition, handgrip strength was significantly associated with mortality and hospitalization in men and with hospitalization in women. Handgrip strength could be a prognostic indicator for health as well as a diagnostic marker of skeletal muscle mass loss in Japanese patients with type 2 diabetes.Hidetaka HamasakiYu KawashimaHisayuki KatsuyamaAkahito SakoAtsushi GotoHidekatsu YanaiNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Hidetaka Hamasaki Yu Kawashima Hisayuki Katsuyama Akahito Sako Atsushi Goto Hidekatsu Yanai Association of handgrip strength with hospitalization, cardiovascular events, and mortality in Japanese patients with type 2 diabetes
description	Abstract Handgrip strength is useful for the diagnosis of sarcopenia. We examined the associations of handgrip strength with all-cause mortality, cardiovascular events, and hospitalization in patients with type 2 diabetes. From April 2013 to December 2015, we conducted a retrospective cohort study to examine patients with type 2 diabetes whose handgrip strength was measured at our hospital. All patients were followed up until May 2016. A total of 1,282 patients (63.8 ± 13.9 years) were enrolled and followed up for 2.36 ± 0.73 years. During the follow-up period, 20 patients (1.6%) died, 14 (1.1%) experienced cardiovascular events, and 556 (43.4%) were admitted to our hospital for any diseases. Multiple regression analyses revealed that handgrip strength was favorably associated with abdominal obesity and renal function. Moreover, Cox proportional hazard analyses with adjustment for potential confounding variables revealed that handgrip strength was significantly associated with occurrence of CVD events and hospitalization in all subjects. In addition, handgrip strength was significantly associated with mortality and hospitalization in men and with hospitalization in women. Handgrip strength could be a prognostic indicator for health as well as a diagnostic marker of skeletal muscle mass loss in Japanese patients with type 2 diabetes.
format	article
author	Hidetaka Hamasaki Yu Kawashima Hisayuki Katsuyama Akahito Sako Atsushi Goto Hidekatsu Yanai
author_facet	Hidetaka Hamasaki Yu Kawashima Hisayuki Katsuyama Akahito Sako Atsushi Goto Hidekatsu Yanai
author_sort	Hidetaka Hamasaki
title	Association of handgrip strength with hospitalization, cardiovascular events, and mortality in Japanese patients with type 2 diabetes
title_short	Association of handgrip strength with hospitalization, cardiovascular events, and mortality in Japanese patients with type 2 diabetes
title_full	Association of handgrip strength with hospitalization, cardiovascular events, and mortality in Japanese patients with type 2 diabetes
title_fullStr	Association of handgrip strength with hospitalization, cardiovascular events, and mortality in Japanese patients with type 2 diabetes
title_full_unstemmed	Association of handgrip strength with hospitalization, cardiovascular events, and mortality in Japanese patients with type 2 diabetes
title_sort	association of handgrip strength with hospitalization, cardiovascular events, and mortality in japanese patients with type 2 diabetes
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/fb252b70002c4ac29cfed1cd525fe395
work_keys_str_mv	AT hidetakahamasaki associationofhandgripstrengthwithhospitalizationcardiovasculareventsandmortalityinjapanesepatientswithtype2diabetes AT yukawashima associationofhandgripstrengthwithhospitalizationcardiovasculareventsandmortalityinjapanesepatientswithtype2diabetes AT hisayukikatsuyama associationofhandgripstrengthwithhospitalizationcardiovasculareventsandmortalityinjapanesepatientswithtype2diabetes AT akahitosako associationofhandgripstrengthwithhospitalizationcardiovasculareventsandmortalityinjapanesepatientswithtype2diabetes AT atsushigoto associationofhandgripstrengthwithhospitalizationcardiovasculareventsandmortalityinjapanesepatientswithtype2diabetes AT hidekatsuyanai associationofhandgripstrengthwithhospitalizationcardiovasculareventsandmortalityinjapanesepatientswithtype2diabetes
_version_	1718384756441219072

Association of handgrip strength with hospitalization, cardiovascular events, and mortality in Japanese patients with type 2 diabetes

Ejemplares similares