Shu complex SWS1-SWSAP1 promotes early steps in mouse meiotic recombination
Homologous recombination ensures genome integrity during meiotic recombination. Here the authors reveal that factors SWS1 and SWSAP1 are critical for meiotic homologues recombination, particularly in promoting assembly of RAD51 and DMC1 on early recombination intermediates.
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Nature Portfolio
2018
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oai:doaj.org-article:fb252f8a69784ca2afef952f285a32f52021-12-02T15:33:57ZShu complex SWS1-SWSAP1 promotes early steps in mouse meiotic recombination10.1038/s41467-018-06384-x2041-1723https://doaj.org/article/fb252f8a69784ca2afef952f285a32f52018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06384-xhttps://doaj.org/toc/2041-1723Homologous recombination ensures genome integrity during meiotic recombination. Here the authors reveal that factors SWS1 and SWSAP1 are critical for meiotic homologues recombination, particularly in promoting assembly of RAD51 and DMC1 on early recombination intermediates.Carla M. AbreuRohit PrakashPeter J. RomanienkoIgnasi RoigScott KeeneyMaria JasinNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018) |
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Science Q Carla M. Abreu Rohit Prakash Peter J. Romanienko Ignasi Roig Scott Keeney Maria Jasin Shu complex SWS1-SWSAP1 promotes early steps in mouse meiotic recombination |
description |
Homologous recombination ensures genome integrity during meiotic recombination. Here the authors reveal that factors SWS1 and SWSAP1 are critical for meiotic homologues recombination, particularly in promoting assembly of RAD51 and DMC1 on early recombination intermediates. |
format |
article |
author |
Carla M. Abreu Rohit Prakash Peter J. Romanienko Ignasi Roig Scott Keeney Maria Jasin |
author_facet |
Carla M. Abreu Rohit Prakash Peter J. Romanienko Ignasi Roig Scott Keeney Maria Jasin |
author_sort |
Carla M. Abreu |
title |
Shu complex SWS1-SWSAP1 promotes early steps in mouse meiotic recombination |
title_short |
Shu complex SWS1-SWSAP1 promotes early steps in mouse meiotic recombination |
title_full |
Shu complex SWS1-SWSAP1 promotes early steps in mouse meiotic recombination |
title_fullStr |
Shu complex SWS1-SWSAP1 promotes early steps in mouse meiotic recombination |
title_full_unstemmed |
Shu complex SWS1-SWSAP1 promotes early steps in mouse meiotic recombination |
title_sort |
shu complex sws1-swsap1 promotes early steps in mouse meiotic recombination |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/fb252f8a69784ca2afef952f285a32f5 |
work_keys_str_mv |
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_version_ |
1718387001005178880 |