Shu complex SWS1-SWSAP1 promotes early steps in mouse meiotic recombination

Homologous recombination ensures genome integrity during meiotic recombination. Here the authors reveal that factors SWS1 and SWSAP1 are critical for meiotic homologues recombination, particularly in promoting assembly of RAD51 and DMC1 on early recombination intermediates.

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Autores principales: Carla M. Abreu, Rohit Prakash, Peter J. Romanienko, Ignasi Roig, Scott Keeney, Maria Jasin
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/fb252f8a69784ca2afef952f285a32f5
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spelling oai:doaj.org-article:fb252f8a69784ca2afef952f285a32f52021-12-02T15:33:57ZShu complex SWS1-SWSAP1 promotes early steps in mouse meiotic recombination10.1038/s41467-018-06384-x2041-1723https://doaj.org/article/fb252f8a69784ca2afef952f285a32f52018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06384-xhttps://doaj.org/toc/2041-1723Homologous recombination ensures genome integrity during meiotic recombination. Here the authors reveal that factors SWS1 and SWSAP1 are critical for meiotic homologues recombination, particularly in promoting assembly of RAD51 and DMC1 on early recombination intermediates.Carla M. AbreuRohit PrakashPeter J. RomanienkoIgnasi RoigScott KeeneyMaria JasinNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Carla M. Abreu
Rohit Prakash
Peter J. Romanienko
Ignasi Roig
Scott Keeney
Maria Jasin
Shu complex SWS1-SWSAP1 promotes early steps in mouse meiotic recombination
description Homologous recombination ensures genome integrity during meiotic recombination. Here the authors reveal that factors SWS1 and SWSAP1 are critical for meiotic homologues recombination, particularly in promoting assembly of RAD51 and DMC1 on early recombination intermediates.
format article
author Carla M. Abreu
Rohit Prakash
Peter J. Romanienko
Ignasi Roig
Scott Keeney
Maria Jasin
author_facet Carla M. Abreu
Rohit Prakash
Peter J. Romanienko
Ignasi Roig
Scott Keeney
Maria Jasin
author_sort Carla M. Abreu
title Shu complex SWS1-SWSAP1 promotes early steps in mouse meiotic recombination
title_short Shu complex SWS1-SWSAP1 promotes early steps in mouse meiotic recombination
title_full Shu complex SWS1-SWSAP1 promotes early steps in mouse meiotic recombination
title_fullStr Shu complex SWS1-SWSAP1 promotes early steps in mouse meiotic recombination
title_full_unstemmed Shu complex SWS1-SWSAP1 promotes early steps in mouse meiotic recombination
title_sort shu complex sws1-swsap1 promotes early steps in mouse meiotic recombination
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/fb252f8a69784ca2afef952f285a32f5
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