Atomic structures of anthrax toxin protective antigen channels bound to partially unfolded lethal and edema factors

The bacterial translocase channel anthrax toxin is composed of the protective antigen (PA) that forms a translocase channel and two cytotoxic enzymes: lethal factor (LF) and edema factor (EF), which go through the PA channel to enter host cells. Here the authors provide mechanistic insights into LF...

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Bibliographic Details
Main Authors: Nathan J. Hardenbrook, Shiheng Liu, Kang Zhou, Koyel Ghosal, Z. Hong Zhou, Bryan A. Krantz
Format: article
Language:EN
Published: Nature Portfolio 2020
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Online Access:https://doaj.org/article/fb291522f6ab40dd9882fe0a6ae1849f
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