Down-regulation of cyclin D2 in amyloid β toxicity, inflammation, and Alzheimer’s disease

Código QR

Down-regulation of cyclin D2 in amyloid β toxicity, inflammation, and Alzheimer’s disease

Mostrar otras versiones (1)

In the current study, we analyzed the effects of the systemic inflammatory response (SIR) and amyloid β (Aβ) peptide on the expression of genes encoding cyclins and cyclin-dependent kinase (Cdk) in: (i) PC12 cells overexpressing human beta amyloid precursor protein (βAPP), wild-type (APPwt-PC12), or...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Grzegorz A. Czapski, Magdalena Cieślik, Emilia Białopiotrowicz, Walter J. Lukiw, Joanna B. Strosznajder
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/fb2c608d737546b99b3dce65632b7ad0
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Down-regulation of cyclin D2 in amyloid β toxicity, inflammation, and Alzheimer's disease.
por: Grzegorz A Czapski, et al.
Publicado: (2021)

Glutamate and GABA in Microglia-Neuron Cross-Talk in Alzheimer’s Disease
por: Grzegorz A. Czapski, et al.
Publicado: (2021)

Oligodendrocytes damage in Alzheimer's disease: Beta amyloid toxicity and inflammation
por: ROTH,ALEJANDRO D, et al.
Publicado: (2005)

Ethanol Alleviates Amyloid-β-Induced Toxicity in an Alzheimer’s Disease Model of Caenorhabiditis elegans
por: Shuju Bai, et al.
Publicado: (2021)

Polymorphic structures of Alzheimer's β-amyloid globulomers.
por: Xiang Yu, et al.
Publicado: (2011)

Mitochondrial ubiquitin ligase alleviates Alzheimer’s disease pathology via blocking the toxic amyloid-β oligomer generation
por: Keisuke Takeda, et al.
Publicado: (2021)

Calcium ions promote formation of amyloid β-peptide (1-40) oligomers causally implicated in neuronal toxicity of Alzheimer's disease.
por: Anna Itkin, et al.
Publicado: (2011)

A Luminex assay detects amyloid β oligomers in Alzheimer's disease cerebrospinal fluid.
por: Adrianna Z Herskovits, et al.
Publicado: (2013)

FMN reduces Amyloid-β toxicity in yeast by regulating redox status and cellular metabolism
por: Xin Chen, et al.
Publicado: (2020)

Genetic dissection of down syndrome-associated alterations in APP/amyloid-β biology using mouse models
por: Justin L. Tosh, et al.
Publicado: (2021)

Allopregnanolone promotes regeneration and reduces β-amyloid burden in a preclinical model of Alzheimer's disease.
por: Shuhua Chen, et al.
Publicado: (2011)

Aminostyrylbenzofuran directly reduces oligomeric amyloid-β and reverses cognitive deficits in Alzheimer transgenic mice.
por: Sang-Hyun Lee, et al.
Publicado: (2014)

PLD3 is a neuronal lysosomal phospholipase D associated with β-amyloid plaques and cognitive function in Alzheimer's disease.
por: Alex G Nackenoff, et al.
Publicado: (2021)

Shedding Light on Alzheimer’s β-Amyloidosis: Photosensitized Methylene Blue Inhibits Self-Assembly of β-Amyloid Peptides and Disintegrates Their Aggregates
por: Byung Il Lee, et al.
Publicado: (2017)

Susceptibility of cyclin-dependent kinase inhibitor 1-deficient mice to rheumatoid arthritis arising from interleukin-1β-induced inflammation
por: Yoshinori Takashima, et al.
Publicado: (2021)

TDP-43 interacts with amyloid-β, inhibits fibrillization, and worsens pathology in a model of Alzheimer’s disease
por: Yao-Hsiang Shih, et al.
Publicado: (2020)

Apolipoprotein E: isoform specific differences in tertiary structure and interaction with amyloid-β in human Alzheimer brain.
por: Phillip B Jones, et al.
Publicado: (2011)

Cryo-EM structure and polymorphism of Aβ amyloid fibrils purified from Alzheimer’s brain tissue
por: Marius Kollmer, et al.
Publicado: (2019)

A cocoa peptide protects Caenorhabditis elegans from oxidative stress and β-amyloid peptide toxicity.
por: Patricia Martorell, et al.
Publicado: (2013)

Dissecting the Crosstalk between Endothelial Mitochondrial Damage, Vascular Inflammation, and Neurodegeneration in Cerebral Amyloid Angiopathy and Alzheimer’s Disease
por: Rebecca M. Parodi-Rullán, et al.
Publicado: (2021)

Publisher Correction: Genetic dissection of down syndrome‑associated alterations in APP/amyloid‑β biology using mouse models
por: Justin L. Tosh, et al.
Publicado: (2021)

Phosphorylation modifies the molecular stability of β-amyloid deposits
por: Nasrollah Rezaei-Ghaleh, et al.
Publicado: (2016)

Amyloid-β42/40 ratio drives tau pathology in 3D human neural cell culture models of Alzheimer’s disease
por: Sang Su Kwak, et al.
Publicado: (2020)

Aβ34 is a BACE1-derived degradation intermediate associated with amyloid clearance and Alzheimer’s disease progression
por: Filip Liebsch, et al.
Publicado: (2019)

Structure of amyloid-β (20-34) with Alzheimer’s-associated isomerization at Asp23 reveals a distinct protofilament interface
por: Rebeccah A. Warmack, et al.
Publicado: (2019)

Dual-targeted carbon-dot-drugs nanoassemblies for modulating Alzheimer's related amyloid-β aggregation and inhibiting fungal infection
por: Chaoren Yan, et al.
Publicado: (2021)

Development of novel 123I-labeled pyridyl benzofuran derivatives for SPECT imaging of β-amyloid plaques in Alzheimer's disease.
por: Masahiro Ono, et al.
Publicado: (2013)

Targeting Apolipoprotein E/Amyloid β Binding by Peptoid CPO_Aβ17-21 P Ameliorates Alzheimer’s Disease Related Pathology and Cognitive Decline
por: Shan Liu, et al.
Publicado: (2017)

Computational design of new Peptide inhibitors for amyloid Beta (aβ) aggregation in Alzheimer's disease: application of a novel methodology.
por: Gözde Eskici, et al.
Publicado: (2013)

Dysregulated expression levels of APH1B in peripheral blood are associated with brain atrophy and amyloid-β deposition in Alzheimer’s disease
por: Young Ho Park, et al.
Publicado: (2021)

CyclinPred: a SVM-based method for predicting cyclin protein sequences.
por: Mridul K Kalita, et al.
Publicado: (2008)

Generation of amyloid-β is reduced by the interaction of calreticulin with amyloid precursor protein, presenilin and nicastrin.
por: Nina Stemmer, et al.
Publicado: (2013)

Relationship between Amyloid-β Deposition and the Coupling between Structural and Functional Brain Networks in Patients with Mild Cognitive Impairment and Alzheimer’s Disease
por: Hui Zhang, et al.
Publicado: (2021)

Degradation of insulin amyloid by antibiotic minocycline and formation of toxic intermediates
por: Wakako Mori, et al.
Publicado: (2021)

The role of heat shock protein 70 in the protective effect of YC-1 on β-amyloid-induced toxicity in differentiated PC12 cells.
por: Yung-Chieh Tsai, et al.
Publicado: (2013)

Lipocalin‐Type Prostaglandin d Synthase Conjugates as Magnetic Resonance Imaging Contrast Agents for Detecting Amyloid β‐Rich Regions in the Brain of Live Alzheimer's Disease Mice
por: Bhargy Sharma, et al.
Publicado: (2021)

MicroRNA-195 inhibits the proliferation of human glioma cells by directly targeting cyclin D1 and cyclin E1.
por: Wang Hui, et al.
Publicado: (2013)

Microbiota-Derived β-Amyloid-like Peptides Trigger Alzheimer’s Disease-Related Pathways in the SH-SY5Y Neural Cell Line
por: Aitor Blanco-Míguez, et al.
Publicado: (2021)

Neuronal microRNA deregulation in response to Alzheimer's disease amyloid-beta.
por: Nicole Schonrock, et al.
Publicado: (2010)

Cyclin G2 suppresses estrogen-mediated osteogenesis through inhibition of Wnt/β-catenin signaling.
por: Jinlan Gao, et al.
Publicado: (2014)