Endoscopic vs. microscopic transsphenoidal pituitary surgery: a single centre study

Abstract Endoscopic pituitary surgery has shown promising results. This study reports the experiences of experienced microscopic pituitary surgeons changing to the endoscopic technique, and the beneficial effects on the postoperative outcomes. 45 transsphenoidal endoscopic-assisted surgeries perform...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Morten Winkler Møller, Marianne Skovsager Andersen, Dorte Glintborg, Christian Bonde Pedersen, Bo Halle, Bjarne Winther Kristensen, Frantz Rom Poulsen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/fb2faa39aac847bfa14ab665708f08fe
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:fb2faa39aac847bfa14ab665708f08fe
record_format	dspace
spelling	oai:doaj.org-article:fb2faa39aac847bfa14ab665708f08fe2021-12-02T13:58:13ZEndoscopic vs. microscopic transsphenoidal pituitary surgery: a single centre study10.1038/s41598-020-78823-z2045-2322https://doaj.org/article/fb2faa39aac847bfa14ab665708f08fe2020-12-01T00:00:00Zhttps://doi.org/10.1038/s41598-020-78823-zhttps://doaj.org/toc/2045-2322Abstract Endoscopic pituitary surgery has shown promising results. This study reports the experiences of experienced microscopic pituitary surgeons changing to the endoscopic technique, and the beneficial effects on the postoperative outcomes. 45 transsphenoidal endoscopic-assisted surgeries performed in 2016–2017 were compared with 195 microscope-assisted surgeries performed in 2007–2017 for pituitary adenoma. Tumour size, hormonal status and vision were assessed preoperatively and 3–5 months postoperatively. Cases were identified through electronic patient records. GTR was achieved in 39% of the endoscopic operations vs. 22% of microscopic operations, p = 0.018. Mean duration of surgery was 86 min (77–95) with the endoscopic technique vs. 106 min (101–111) with the microscopic technique, p < 0.001. New hypothalamus–pituitary–adrenal axis deficiencies were observed after 3% of endoscopic vs. 34% microscopic operations, p = 0.001, and overall fewer postoperative pituitary deficiencies were observed in the endoscope-assisted group. Complications within 30 days of surgery occurred in 17% of endoscopic operations vs. 27% of microscopic operations (p > 0.05). Normalization of visual impairment occurred in 37% of the cases with preoperative visual impairment in the endoscopic group vs. 35% of those in the microscopic group (p > 0.05). The endoscopic technique performed better as a surgical procedure for pituitary adenomas. We found no statistically significant differences in complication rate or visual improvement between the two techniques.Morten Winkler MøllerMarianne Skovsager AndersenDorte GlintborgChristian Bonde PedersenBo HalleBjarne Winther KristensenFrantz Rom PoulsenNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Morten Winkler Møller Marianne Skovsager Andersen Dorte Glintborg Christian Bonde Pedersen Bo Halle Bjarne Winther Kristensen Frantz Rom Poulsen Endoscopic vs. microscopic transsphenoidal pituitary surgery: a single centre study
description	Abstract Endoscopic pituitary surgery has shown promising results. This study reports the experiences of experienced microscopic pituitary surgeons changing to the endoscopic technique, and the beneficial effects on the postoperative outcomes. 45 transsphenoidal endoscopic-assisted surgeries performed in 2016–2017 were compared with 195 microscope-assisted surgeries performed in 2007–2017 for pituitary adenoma. Tumour size, hormonal status and vision were assessed preoperatively and 3–5 months postoperatively. Cases were identified through electronic patient records. GTR was achieved in 39% of the endoscopic operations vs. 22% of microscopic operations, p = 0.018. Mean duration of surgery was 86 min (77–95) with the endoscopic technique vs. 106 min (101–111) with the microscopic technique, p < 0.001. New hypothalamus–pituitary–adrenal axis deficiencies were observed after 3% of endoscopic vs. 34% microscopic operations, p = 0.001, and overall fewer postoperative pituitary deficiencies were observed in the endoscope-assisted group. Complications within 30 days of surgery occurred in 17% of endoscopic operations vs. 27% of microscopic operations (p > 0.05). Normalization of visual impairment occurred in 37% of the cases with preoperative visual impairment in the endoscopic group vs. 35% of those in the microscopic group (p > 0.05). The endoscopic technique performed better as a surgical procedure for pituitary adenomas. We found no statistically significant differences in complication rate or visual improvement between the two techniques.
format	article
author	Morten Winkler Møller Marianne Skovsager Andersen Dorte Glintborg Christian Bonde Pedersen Bo Halle Bjarne Winther Kristensen Frantz Rom Poulsen
author_facet	Morten Winkler Møller Marianne Skovsager Andersen Dorte Glintborg Christian Bonde Pedersen Bo Halle Bjarne Winther Kristensen Frantz Rom Poulsen
author_sort	Morten Winkler Møller
title	Endoscopic vs. microscopic transsphenoidal pituitary surgery: a single centre study
title_short	Endoscopic vs. microscopic transsphenoidal pituitary surgery: a single centre study
title_full	Endoscopic vs. microscopic transsphenoidal pituitary surgery: a single centre study
title_fullStr	Endoscopic vs. microscopic transsphenoidal pituitary surgery: a single centre study
title_full_unstemmed	Endoscopic vs. microscopic transsphenoidal pituitary surgery: a single centre study
title_sort	endoscopic vs. microscopic transsphenoidal pituitary surgery: a single centre study
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/fb2faa39aac847bfa14ab665708f08fe
work_keys_str_mv	AT mortenwinklermøller endoscopicvsmicroscopictranssphenoidalpituitarysurgeryasinglecentrestudy AT marianneskovsagerandersen endoscopicvsmicroscopictranssphenoidalpituitarysurgeryasinglecentrestudy AT dorteglintborg endoscopicvsmicroscopictranssphenoidalpituitarysurgeryasinglecentrestudy AT christianbondepedersen endoscopicvsmicroscopictranssphenoidalpituitarysurgeryasinglecentrestudy AT bohalle endoscopicvsmicroscopictranssphenoidalpituitarysurgeryasinglecentrestudy AT bjarnewintherkristensen endoscopicvsmicroscopictranssphenoidalpituitarysurgeryasinglecentrestudy AT frantzrompoulsen endoscopicvsmicroscopictranssphenoidalpituitarysurgeryasinglecentrestudy
_version_	1718392238428389376

Endoscopic vs. microscopic transsphenoidal pituitary surgery: a single centre study

Ejemplares similares