A vaccinia-based single vector construct multi-pathogen vaccine protects against both Zika and chikungunya viruses
Zika and chikungunya virus are co-circulating in many regions and currently there is no approved vaccine for either virus. Here, the authors engineer one vaccinia virus based vaccine for both, Zika and chikungunya, and show protection from infection and pathogenesis in mice.
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Nature Portfolio
2018
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oai:doaj.org-article:fb33c22d0fd945c1b4999adae6928f2c2021-12-02T14:38:48ZA vaccinia-based single vector construct multi-pathogen vaccine protects against both Zika and chikungunya viruses10.1038/s41467-018-03662-62041-1723https://doaj.org/article/fb33c22d0fd945c1b4999adae6928f2c2018-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03662-6https://doaj.org/toc/2041-1723Zika and chikungunya virus are co-circulating in many regions and currently there is no approved vaccine for either virus. Here, the authors engineer one vaccinia virus based vaccine for both, Zika and chikungunya, and show protection from infection and pathogenesis in mice.Natalie A. ProwLiang LiuEri NakayamaTamara H. CooperKexin YanPreethi EldiJessamine E. HazlewoodBing TangThuy T. LeYin Xiang SetohAlexander A KhromykhJody Hobson-PetersKerrilyn R. DienerPaul M. HowleyJohn D. HayballAndreas SuhrbierNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Natalie A. Prow Liang Liu Eri Nakayama Tamara H. Cooper Kexin Yan Preethi Eldi Jessamine E. Hazlewood Bing Tang Thuy T. Le Yin Xiang Setoh Alexander A Khromykh Jody Hobson-Peters Kerrilyn R. Diener Paul M. Howley John D. Hayball Andreas Suhrbier A vaccinia-based single vector construct multi-pathogen vaccine protects against both Zika and chikungunya viruses |
| description |
Zika and chikungunya virus are co-circulating in many regions and currently there is no approved vaccine for either virus. Here, the authors engineer one vaccinia virus based vaccine for both, Zika and chikungunya, and show protection from infection and pathogenesis in mice. |
| format |
article |
| author |
Natalie A. Prow Liang Liu Eri Nakayama Tamara H. Cooper Kexin Yan Preethi Eldi Jessamine E. Hazlewood Bing Tang Thuy T. Le Yin Xiang Setoh Alexander A Khromykh Jody Hobson-Peters Kerrilyn R. Diener Paul M. Howley John D. Hayball Andreas Suhrbier |
| author_facet |
Natalie A. Prow Liang Liu Eri Nakayama Tamara H. Cooper Kexin Yan Preethi Eldi Jessamine E. Hazlewood Bing Tang Thuy T. Le Yin Xiang Setoh Alexander A Khromykh Jody Hobson-Peters Kerrilyn R. Diener Paul M. Howley John D. Hayball Andreas Suhrbier |
| author_sort |
Natalie A. Prow |
| title |
A vaccinia-based single vector construct multi-pathogen vaccine protects against both Zika and chikungunya viruses |
| title_short |
A vaccinia-based single vector construct multi-pathogen vaccine protects against both Zika and chikungunya viruses |
| title_full |
A vaccinia-based single vector construct multi-pathogen vaccine protects against both Zika and chikungunya viruses |
| title_fullStr |
A vaccinia-based single vector construct multi-pathogen vaccine protects against both Zika and chikungunya viruses |
| title_full_unstemmed |
A vaccinia-based single vector construct multi-pathogen vaccine protects against both Zika and chikungunya viruses |
| title_sort |
vaccinia-based single vector construct multi-pathogen vaccine protects against both zika and chikungunya viruses |
| publisher |
Nature Portfolio |
| publishDate |
2018 |
| url |
https://doaj.org/article/fb33c22d0fd945c1b4999adae6928f2c |
| work_keys_str_mv |
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