Identification of proteins and miRNAs that specifically bind an mRNA in vivo
The entire mRNA interactome capture has been established but identification of specific mRNA-binding proteins has been challenging. Here, the authors developed an in vivo RNA–protein crosslinking and RNA pulldown approach and characterized novel interactors of the C. elegans gld-1 mRNA, including DA...
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Autores principales: | Kathrin Theil, Koshi Imami, Nikolaus Rajewsky |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
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Materias: | |
Acceso en línea: | https://doaj.org/article/fb430fe1570143bcbdaa03bc4370fae0 |
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