Identification of proteins and miRNAs that specifically bind an mRNA in vivo

The entire mRNA interactome capture has been established but identification of specific mRNA-binding proteins has been challenging. Here, the authors developed an in vivo RNA–protein crosslinking and RNA pulldown approach and characterized novel interactors of the C. elegans gld-1 mRNA, including DA...

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Autores principales: Kathrin Theil, Koshi Imami, Nikolaus Rajewsky
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/fb430fe1570143bcbdaa03bc4370fae0
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