Sleep onset latency is related with reduced bone mineral density in elderly people with insomnia: a retrospective study

Qian Tong,1,2,* Wanzhen Wu,2,* Qing Wu,2 Yanbo Yu,3 Xiaoling Lv,2 Bozhong Wang,2 Guofu Wang1,2 1Zhejiang Chinese Medical University, Hangzhou 310053, Zhejiang, China; 2Department of Geriatrics, Zhejiang Hospital, Zhejiang Provincial Key Lab of Geriatrics, Hangzhou 310013, Zhejiang, China; 3Wenzhou...

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Autores principales:	Tong Q, Wu WZ, Wu Q, Yu YB, Lv XL, Wang BZ, Wang GF
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2018
Materias:	bone mineral density insomnia osteoporosis osteopenia pittsburgh sleep quality index sleep onset latency Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/fb4821acb5a849589fa89b282d3bea11
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spelling	oai:doaj.org-article:fb4821acb5a849589fa89b282d3bea112021-12-02T01:38:16ZSleep onset latency is related with reduced bone mineral density in elderly people with insomnia: a retrospective study1178-1998https://doaj.org/article/fb4821acb5a849589fa89b282d3bea112018-08-01T00:00:00Zhttps://www.dovepress.com/sleep-onset-latency-is-related-with-reduced-bone-mineral-density-in-el-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Qian Tong,1,2,* Wanzhen Wu,2,* Qing Wu,2 Yanbo Yu,3 Xiaoling Lv,2 Bozhong Wang,2 Guofu Wang1,2 1Zhejiang Chinese Medical University, Hangzhou 310053, Zhejiang, China; 2Department of Geriatrics, Zhejiang Hospital, Zhejiang Provincial Key Lab of Geriatrics, Hangzhou 310013, Zhejiang, China; 3Wenzhou Medical University, Wenzhou, 325035 Zhejiang, China *These authors contributed equally to this work Purpose: Inconsistent outcome about association between insufficient sleep and bone mineral density (BMD) has been reported. The present study aimed to determine whether BMD was associated with score of Pittsburgh Sleep Quality Index (PSQI).Methods: A total of 410 patients (mean age 81.6±5.9 years) attending our hospital for evaluation of sleep were retrospectively studied. Dual-Energy X-ray Absorptiometry was used to measure BMD and T-score at femoral neck and lumbar spines over L2–L4 regions. Subjective sleep status was evaluated by the PSQI questionnaires. The Mann–Whitney U test and chi-square analysis were used to compare continuous variables and categorical variables, respectively. Spearman correlation test was conducted to find the relationship between BMD and other clinical factors. Multinomial logistic regressions analysis was performed to analyze independent factors predicting BMD.Results: Majority of the participants with osteoporosis (OP) were female and had lower body mass index (BMI) and higher sleep onset latency score. Spearman correlation test showed that gender, BMI, score of total PSQI, and sleep onset latency were significantly related to BMD and T-score in femoral neck and lumbar region L2–L4. Finally, multinomial logistic regression analysis demonstrated that gender and age were independent factors for OP and osteopenia and that after adjustment for gender, age, and BMI, sleep onset latency of <15 minutes (OR: 0.38; 95% CI: 0.15–0.96; P=0.04) and 16–30 minutes (OR: 0.37; 95% CI: 0.17–0.79; P=0.01) were less likely to have reduced BMD.Conclusion: There was a significant association between BMD and sleep onset latency, suggesting that, in elderly patients with sleep problem, BMD measurement and intervention for OP might be valuable. Keywords: bone mineral density, insomnia, osteoporosis, osteopenia, Pittsburgh Sleep Quality Index, sleep onset latencyTong QWu WZWu QYu YBLv XLWang BZWang GFDove Medical Pressarticlebone mineral densityinsomniaosteoporosisosteopeniapittsburgh sleep quality indexsleep onset latencyGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 13, Pp 1525-1530 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	bone mineral density insomnia osteoporosis osteopenia pittsburgh sleep quality index sleep onset latency Geriatrics RC952-954.6
spellingShingle	bone mineral density insomnia osteoporosis osteopenia pittsburgh sleep quality index sleep onset latency Geriatrics RC952-954.6 Tong Q Wu WZ Wu Q Yu YB Lv XL Wang BZ Wang GF Sleep onset latency is related with reduced bone mineral density in elderly people with insomnia: a retrospective study
description	Qian Tong,1,2,* Wanzhen Wu,2,* Qing Wu,2 Yanbo Yu,3 Xiaoling Lv,2 Bozhong Wang,2 Guofu Wang1,2 1Zhejiang Chinese Medical University, Hangzhou 310053, Zhejiang, China; 2Department of Geriatrics, Zhejiang Hospital, Zhejiang Provincial Key Lab of Geriatrics, Hangzhou 310013, Zhejiang, China; 3Wenzhou Medical University, Wenzhou, 325035 Zhejiang, China *These authors contributed equally to this work Purpose: Inconsistent outcome about association between insufficient sleep and bone mineral density (BMD) has been reported. The present study aimed to determine whether BMD was associated with score of Pittsburgh Sleep Quality Index (PSQI).Methods: A total of 410 patients (mean age 81.6±5.9 years) attending our hospital for evaluation of sleep were retrospectively studied. Dual-Energy X-ray Absorptiometry was used to measure BMD and T-score at femoral neck and lumbar spines over L2–L4 regions. Subjective sleep status was evaluated by the PSQI questionnaires. The Mann–Whitney U test and chi-square analysis were used to compare continuous variables and categorical variables, respectively. Spearman correlation test was conducted to find the relationship between BMD and other clinical factors. Multinomial logistic regressions analysis was performed to analyze independent factors predicting BMD.Results: Majority of the participants with osteoporosis (OP) were female and had lower body mass index (BMI) and higher sleep onset latency score. Spearman correlation test showed that gender, BMI, score of total PSQI, and sleep onset latency were significantly related to BMD and T-score in femoral neck and lumbar region L2–L4. Finally, multinomial logistic regression analysis demonstrated that gender and age were independent factors for OP and osteopenia and that after adjustment for gender, age, and BMI, sleep onset latency of <15 minutes (OR: 0.38; 95% CI: 0.15–0.96; P=0.04) and 16–30 minutes (OR: 0.37; 95% CI: 0.17–0.79; P=0.01) were less likely to have reduced BMD.Conclusion: There was a significant association between BMD and sleep onset latency, suggesting that, in elderly patients with sleep problem, BMD measurement and intervention for OP might be valuable. Keywords: bone mineral density, insomnia, osteoporosis, osteopenia, Pittsburgh Sleep Quality Index, sleep onset latency
format	article
author	Tong Q Wu WZ Wu Q Yu YB Lv XL Wang BZ Wang GF
author_facet	Tong Q Wu WZ Wu Q Yu YB Lv XL Wang BZ Wang GF
author_sort	Tong Q
title	Sleep onset latency is related with reduced bone mineral density in elderly people with insomnia: a retrospective study
title_short	Sleep onset latency is related with reduced bone mineral density in elderly people with insomnia: a retrospective study
title_full	Sleep onset latency is related with reduced bone mineral density in elderly people with insomnia: a retrospective study
title_fullStr	Sleep onset latency is related with reduced bone mineral density in elderly people with insomnia: a retrospective study
title_full_unstemmed	Sleep onset latency is related with reduced bone mineral density in elderly people with insomnia: a retrospective study
title_sort	sleep onset latency is related with reduced bone mineral density in elderly people with insomnia: a retrospective study
publisher	Dove Medical Press
publishDate	2018
url	https://doaj.org/article/fb4821acb5a849589fa89b282d3bea11
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Sleep onset latency is related with reduced bone mineral density in elderly people with insomnia: a retrospective study

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