Microglia-neuron interaction at nodes of Ranvier depends on neuronal activity through potassium release and contributes to remyelination
Microglia are important for brain homeostasis and plasticity. The mechanisms underlying microglia-neuron interactions are still unclear. Here, the authors show that microglia preferentially interact with the nodes of Ranvier along axons. This interaction is modulated by neuronal activity and contrib...
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Main Authors: | R. Ronzano, T. Roux, M. Thetiot, M. S. Aigrot, L. Richard, F. X. Lejeune, E. Mazuir, J. M. Vallat, C. Lubetzki, A. Desmazières |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
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Subjects: | |
Online Access: | https://doaj.org/article/fb4d5db5626f437294c686841cb40c71 |
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