Microglia-neuron interaction at nodes of Ranvier depends on neuronal activity through potassium release and contributes to remyelination
Microglia are important for brain homeostasis and plasticity. The mechanisms underlying microglia-neuron interactions are still unclear. Here, the authors show that microglia preferentially interact with the nodes of Ranvier along axons. This interaction is modulated by neuronal activity and contrib...
Enregistré dans:
Auteurs principaux: | R. Ronzano, T. Roux, M. Thetiot, M. S. Aigrot, L. Richard, F. X. Lejeune, E. Mazuir, J. M. Vallat, C. Lubetzki, A. Desmazières |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2021
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/fb4d5db5626f437294c686841cb40c71 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Nodes of ranvier and paranodes in chronic acquired neuropathies.
par: Carmen Cifuentes-Diaz, et autres
Publié: (2011) -
Optical Read-out of Neural Activity in Mammalian Peripheral Axons: Calcium Signaling at Nodes of Ranvier
par: Arjun K. Fontaine, et autres
Publié: (2017) -
Microglia clear neuron-released α-synuclein via selective autophagy and prevent neurodegeneration
par: Insup Choi, et autres
Publié: (2020) -
Disruption of neuronal autophagy by infected microglia results in neurodegeneration.
par: Mehrdad Alirezaei, et autres
Publié: (2008) -
Neuron-derived CCL2 contributes to microglia activation and neurological decline in hepatic encephalopathy
par: Zhang,Li, et autres
Publié: (2017)