The molecular basis of phosphite and hypophosphite recognition by ABC-transporters

Some bacteria can use inorganic phosphite and hypophosphite as sources of inorganic phosphorus. Here, the authors report crystal structures of the periplasmic proteins that bind these reduced phosphorus species and show that a P-H…π interaction between the ligand and binding site determines their sp...

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Autores principales:	Claudine Bisson, Nathan B. P. Adams, Ben Stevenson, Amanda A. Brindley, Despo Polyviou, Thomas S. Bibby, Patrick J. Baker, C. Neil Hunter, Andrew Hitchcock
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/fb628c898a23417e81de94e06a980504
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spelling	oai:doaj.org-article:fb628c898a23417e81de94e06a9805042021-12-02T15:38:42ZThe molecular basis of phosphite and hypophosphite recognition by ABC-transporters10.1038/s41467-017-01226-82041-1723https://doaj.org/article/fb628c898a23417e81de94e06a9805042017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01226-8https://doaj.org/toc/2041-1723Some bacteria can use inorganic phosphite and hypophosphite as sources of inorganic phosphorus. Here, the authors report crystal structures of the periplasmic proteins that bind these reduced phosphorus species and show that a P-H…π interaction between the ligand and binding site determines their specificity.Claudine BissonNathan B. P. AdamsBen StevensonAmanda A. BrindleyDespo PolyviouThomas S. BibbyPatrick J. BakerC. Neil HunterAndrew HitchcockNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Claudine Bisson Nathan B. P. Adams Ben Stevenson Amanda A. Brindley Despo Polyviou Thomas S. Bibby Patrick J. Baker C. Neil Hunter Andrew Hitchcock The molecular basis of phosphite and hypophosphite recognition by ABC-transporters
description	Some bacteria can use inorganic phosphite and hypophosphite as sources of inorganic phosphorus. Here, the authors report crystal structures of the periplasmic proteins that bind these reduced phosphorus species and show that a P-H…π interaction between the ligand and binding site determines their specificity.
format	article
author	Claudine Bisson Nathan B. P. Adams Ben Stevenson Amanda A. Brindley Despo Polyviou Thomas S. Bibby Patrick J. Baker C. Neil Hunter Andrew Hitchcock
author_facet	Claudine Bisson Nathan B. P. Adams Ben Stevenson Amanda A. Brindley Despo Polyviou Thomas S. Bibby Patrick J. Baker C. Neil Hunter Andrew Hitchcock
author_sort	Claudine Bisson
title	The molecular basis of phosphite and hypophosphite recognition by ABC-transporters
title_short	The molecular basis of phosphite and hypophosphite recognition by ABC-transporters
title_full	The molecular basis of phosphite and hypophosphite recognition by ABC-transporters
title_fullStr	The molecular basis of phosphite and hypophosphite recognition by ABC-transporters
title_full_unstemmed	The molecular basis of phosphite and hypophosphite recognition by ABC-transporters
title_sort	molecular basis of phosphite and hypophosphite recognition by abc-transporters
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/fb628c898a23417e81de94e06a980504
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The molecular basis of phosphite and hypophosphite recognition by ABC-transporters

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