Optogenetic manipulation of calcium signals in single T cells in vivo

The ability to manipulate and monitor calcium signaling in cells in vivo would provide insights into signaling in an endogenous context. Here the authors develop a two-photon-responsive calcium actuator and reporter combination to monitor the effect of calcium actuation on T cell migration, adhesion...

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Autores principales: Armelle Bohineust, Zacarias Garcia, Béatrice Corre, Fabrice Lemaître, Philippe Bousso
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/fb7b30514bec4ff1a467119ddb06597e
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