Mycobacterium tuberculosis ClpP proteases are co-transcribed but exhibit different substrate specificities.
Caseinolytic (Clp) proteases are widespread energy-dependent proteases; the functional ATP-dependent protease is comprised of multimers of proteolytic and regulatory subunits. Mycobacterium tuberculosis has two ClpP proteolytic subunits (ClpP1 and ClpP2), with both being essential for growth in vitr...
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Main Authors: | Yoann Personne, Amanda C Brown, Dorothée L Schuessler, Tanya Parish |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2013
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Online Access: | https://doaj.org/article/fb88543b5e7d478ea129b1e11c72688b |
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