Mycobacterium tuberculosis ClpP proteases are co-transcribed but exhibit different substrate specificities.
Caseinolytic (Clp) proteases are widespread energy-dependent proteases; the functional ATP-dependent protease is comprised of multimers of proteolytic and regulatory subunits. Mycobacterium tuberculosis has two ClpP proteolytic subunits (ClpP1 and ClpP2), with both being essential for growth in vitr...
Enregistré dans:
Auteurs principaux: | Yoann Personne, Amanda C Brown, Dorothée L Schuessler, Tanya Parish |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2013
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/fb88543b5e7d478ea129b1e11c72688b |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Post-translational regulation via Clp protease is critical for survival of Mycobacterium tuberculosis.
par: Ravikiran M Raju, et autres
Publié: (2014) -
Cell Division Protein FtsZ Is Unfolded for N-Terminal Degradation by Antibiotic-Activated ClpP
par: Nadine Silber, et autres
Publié: (2020) -
The ClpX and ClpP2 Orthologs of <named-content content-type="genus-species">Chlamydia trachomatis</named-content> Perform Discrete and Essential Functions in Organism Growth and Development
par: Nicholas A. Wood, et autres
Publié: (2020) -
Regulation of Antimycin Biosynthesis Is Controlled by the ClpXP Protease
par: Bohdan Bilyk, et autres
Publié: (2020) -
Structural basis for substrate gripping and translocation by the ClpB AAA+ disaggregase
par: Alexandrea N. Rizo, et autres
Publié: (2019)