Mycobacterium tuberculosis ClpP proteases are co-transcribed but exhibit different substrate specificities.

Caseinolytic (Clp) proteases are widespread energy-dependent proteases; the functional ATP-dependent protease is comprised of multimers of proteolytic and regulatory subunits. Mycobacterium tuberculosis has two ClpP proteolytic subunits (ClpP1 and ClpP2), with both being essential for growth in vitr...

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Autores principales: Yoann Personne, Amanda C Brown, Dorothée L Schuessler, Tanya Parish
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/fb88543b5e7d478ea129b1e11c72688b
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