Vaginal microbiota during the menopausal transition: the role of lactobacilli

Physiological loss of ovarian function during the menopausal transition often leads to the development of unfavorable symptoms associated with vulvovaginal atrophy, recurrent urinary tract infections and dyspareunia. Currently, the scientific community is actively discussing the risks and benefits o...

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Autores principales: Yulia E. Dobrokhotova, Polina A. Shadrova, Vladimir I. Komagorov
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Lenguaje:RU
Publicado: IP Berlin A.V. 2021
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Acceso en línea:https://doaj.org/article/fb8d4d393de940de89e3fdb139b95879
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spelling oai:doaj.org-article:fb8d4d393de940de89e3fdb139b958792021-12-02T19:22:24ZVaginal microbiota during the menopausal transition: the role of lactobacilli2079-56962079-583110.26442/20795696.2021.3.200905https://doaj.org/article/fb8d4d393de940de89e3fdb139b958792021-08-01T00:00:00Zhttps://gynecology.orscience.ru/2079-5831/article/viewFile/76088/56684https://doaj.org/toc/2079-5696https://doaj.org/toc/2079-5831Physiological loss of ovarian function during the menopausal transition often leads to the development of unfavorable symptoms associated with vulvovaginal atrophy, recurrent urinary tract infections and dyspareunia. Currently, the scientific community is actively discussing the risks and benefits of prescribing menopausal hormone therapy to relieve the consequences of estrogen deficiency. The study of vaginal microbiota in dynamics made it possible to take a deeper look at the development of genitourinary menopausal syndrome and associate several microorganisms with specific undesirable manifestations. The link between recurrent urinary tract infections during menopause and physiological replacement of microbiota by opportunistic flora with the development of unpleasant symptoms resolves doctors to resort to irrational courses of antibiotic therapy. The review is devoted to the generalization of information on microbiological changes in the vagina during perimenopause, the possibilities of choosing the optimal hormone therapy for the correction of symptoms, the use of new promising methods, including management by modulating the vaginal microbiota.Yulia E. DobrokhotovaPolina A. ShadrovaVladimir I. KomagorovIP Berlin A.V. articlemenopausemenopausal hormone therapyestrogen deficiencyvaginal microbiotalactobacilligenitourinary syndromevulvovaginal atrophyGynecology and obstetricsRG1-991RUГинекология, Vol 23, Iss 3, Pp 214-221 (2021)
institution DOAJ
collection DOAJ
language RU
topic menopause
menopausal hormone therapy
estrogen deficiency
vaginal microbiota
lactobacilli
genitourinary syndrome
vulvovaginal atrophy
Gynecology and obstetrics
RG1-991
spellingShingle menopause
menopausal hormone therapy
estrogen deficiency
vaginal microbiota
lactobacilli
genitourinary syndrome
vulvovaginal atrophy
Gynecology and obstetrics
RG1-991
Yulia E. Dobrokhotova
Polina A. Shadrova
Vladimir I. Komagorov
Vaginal microbiota during the menopausal transition: the role of lactobacilli
description Physiological loss of ovarian function during the menopausal transition often leads to the development of unfavorable symptoms associated with vulvovaginal atrophy, recurrent urinary tract infections and dyspareunia. Currently, the scientific community is actively discussing the risks and benefits of prescribing menopausal hormone therapy to relieve the consequences of estrogen deficiency. The study of vaginal microbiota in dynamics made it possible to take a deeper look at the development of genitourinary menopausal syndrome and associate several microorganisms with specific undesirable manifestations. The link between recurrent urinary tract infections during menopause and physiological replacement of microbiota by opportunistic flora with the development of unpleasant symptoms resolves doctors to resort to irrational courses of antibiotic therapy. The review is devoted to the generalization of information on microbiological changes in the vagina during perimenopause, the possibilities of choosing the optimal hormone therapy for the correction of symptoms, the use of new promising methods, including management by modulating the vaginal microbiota.
format article
author Yulia E. Dobrokhotova
Polina A. Shadrova
Vladimir I. Komagorov
author_facet Yulia E. Dobrokhotova
Polina A. Shadrova
Vladimir I. Komagorov
author_sort Yulia E. Dobrokhotova
title Vaginal microbiota during the menopausal transition: the role of lactobacilli
title_short Vaginal microbiota during the menopausal transition: the role of lactobacilli
title_full Vaginal microbiota during the menopausal transition: the role of lactobacilli
title_fullStr Vaginal microbiota during the menopausal transition: the role of lactobacilli
title_full_unstemmed Vaginal microbiota during the menopausal transition: the role of lactobacilli
title_sort vaginal microbiota during the menopausal transition: the role of lactobacilli
publisher IP Berlin A.V.
publishDate 2021
url https://doaj.org/article/fb8d4d393de940de89e3fdb139b95879
work_keys_str_mv AT yuliaedobrokhotova vaginalmicrobiotaduringthemenopausaltransitiontheroleoflactobacilli
AT polinaashadrova vaginalmicrobiotaduringthemenopausaltransitiontheroleoflactobacilli
AT vladimirikomagorov vaginalmicrobiotaduringthemenopausaltransitiontheroleoflactobacilli
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