Excitatory VTA to DH projections provide a valence signal to memory circuits

The neuronal pathway that signals the positive or negative value of memories is not well understood. Here, the authors report that an excitatory projection from the ventral tegmental area to the dorsal hippocampus carries the valence information, contributing, especially in females, to the recurrenc...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Yuan Han, Yi Zhang, Haram Kim, Viktoriya S. Grayson, Vladimir Jovasevic, Wenjie Ren, Maria V. Centeno, Anita L. Guedea, Mariah A. A. Meyer, Yixin Wu, Philipp Gutruf, Dalton J. Surmeier, Can Gao, Marco Martina, Apkar V. Apkarian, John A. Rogers, Jelena Radulovic
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/fb93f000603a4b0ab4d46be2b445e93f
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:fb93f000603a4b0ab4d46be2b445e93f
record_format	dspace
spelling	oai:doaj.org-article:fb93f000603a4b0ab4d46be2b445e93f2021-12-02T15:39:21ZExcitatory VTA to DH projections provide a valence signal to memory circuits10.1038/s41467-020-15035-z2041-1723https://doaj.org/article/fb93f000603a4b0ab4d46be2b445e93f2020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15035-zhttps://doaj.org/toc/2041-1723The neuronal pathway that signals the positive or negative value of memories is not well understood. Here, the authors report that an excitatory projection from the ventral tegmental area to the dorsal hippocampus carries the valence information, contributing, especially in females, to the recurrence of fear and to drug seeking behavior.Yuan HanYi ZhangHaram KimViktoriya S. GraysonVladimir JovasevicWenjie RenMaria V. CentenoAnita L. GuedeaMariah A. A. MeyerYixin WuPhilipp GutrufDalton J. SurmeierCan GaoMarco MartinaApkar V. ApkarianJohn A. RogersJelena RadulovicNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yuan Han Yi Zhang Haram Kim Viktoriya S. Grayson Vladimir Jovasevic Wenjie Ren Maria V. Centeno Anita L. Guedea Mariah A. A. Meyer Yixin Wu Philipp Gutruf Dalton J. Surmeier Can Gao Marco Martina Apkar V. Apkarian John A. Rogers Jelena Radulovic Excitatory VTA to DH projections provide a valence signal to memory circuits
description	The neuronal pathway that signals the positive or negative value of memories is not well understood. Here, the authors report that an excitatory projection from the ventral tegmental area to the dorsal hippocampus carries the valence information, contributing, especially in females, to the recurrence of fear and to drug seeking behavior.
format	article
author	Yuan Han Yi Zhang Haram Kim Viktoriya S. Grayson Vladimir Jovasevic Wenjie Ren Maria V. Centeno Anita L. Guedea Mariah A. A. Meyer Yixin Wu Philipp Gutruf Dalton J. Surmeier Can Gao Marco Martina Apkar V. Apkarian John A. Rogers Jelena Radulovic
author_facet	Yuan Han Yi Zhang Haram Kim Viktoriya S. Grayson Vladimir Jovasevic Wenjie Ren Maria V. Centeno Anita L. Guedea Mariah A. A. Meyer Yixin Wu Philipp Gutruf Dalton J. Surmeier Can Gao Marco Martina Apkar V. Apkarian John A. Rogers Jelena Radulovic
author_sort	Yuan Han
title	Excitatory VTA to DH projections provide a valence signal to memory circuits
title_short	Excitatory VTA to DH projections provide a valence signal to memory circuits
title_full	Excitatory VTA to DH projections provide a valence signal to memory circuits
title_fullStr	Excitatory VTA to DH projections provide a valence signal to memory circuits
title_full_unstemmed	Excitatory VTA to DH projections provide a valence signal to memory circuits
title_sort	excitatory vta to dh projections provide a valence signal to memory circuits
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/fb93f000603a4b0ab4d46be2b445e93f
work_keys_str_mv	AT yuanhan excitatoryvtatodhprojectionsprovideavalencesignaltomemorycircuits AT yizhang excitatoryvtatodhprojectionsprovideavalencesignaltomemorycircuits AT haramkim excitatoryvtatodhprojectionsprovideavalencesignaltomemorycircuits AT viktoriyasgrayson excitatoryvtatodhprojectionsprovideavalencesignaltomemorycircuits AT vladimirjovasevic excitatoryvtatodhprojectionsprovideavalencesignaltomemorycircuits AT wenjieren excitatoryvtatodhprojectionsprovideavalencesignaltomemorycircuits AT mariavcenteno excitatoryvtatodhprojectionsprovideavalencesignaltomemorycircuits AT anitalguedea excitatoryvtatodhprojectionsprovideavalencesignaltomemorycircuits AT mariahaameyer excitatoryvtatodhprojectionsprovideavalencesignaltomemorycircuits AT yixinwu excitatoryvtatodhprojectionsprovideavalencesignaltomemorycircuits AT philippgutruf excitatoryvtatodhprojectionsprovideavalencesignaltomemorycircuits AT daltonjsurmeier excitatoryvtatodhprojectionsprovideavalencesignaltomemorycircuits AT cangao excitatoryvtatodhprojectionsprovideavalencesignaltomemorycircuits AT marcomartina excitatoryvtatodhprojectionsprovideavalencesignaltomemorycircuits AT apkarvapkarian excitatoryvtatodhprojectionsprovideavalencesignaltomemorycircuits AT johnarogers excitatoryvtatodhprojectionsprovideavalencesignaltomemorycircuits AT jelenaradulovic excitatoryvtatodhprojectionsprovideavalencesignaltomemorycircuits
_version_	1718385968672669696

Excitatory VTA to DH projections provide a valence signal to memory circuits

Ejemplares similares