Dose intensity and autologous stem cell transplantation as salvage therapy for pediatric primary CNS malignancies

Seiji Kojima,1 Andrei Cucuianu,2,3 Yoshiyuki Takahashi,1 Ioana Berindan-Neagoe,4–6 Ioan-Stefan Florian,7 Delia Dima,2 Ciprian Tomuleasa2,4 1Department of Paediatrics, Nagoya University Graduate School of Medicine, Nagoya, Japan; 2Department of Hematology, Ion Chiricuta Oncology Institute...

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Autores principales:	Kojima S, Cucuianu A, Takahashi Y, Berindan-Neagoe I, Florian IS, Dima D, Tomuleasa C
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2014
Materias:	Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/fba72393f1934b7795a25aa9deb234c3
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spelling	oai:doaj.org-article:fba72393f1934b7795a25aa9deb234c32021-12-02T00:39:22ZDose intensity and autologous stem cell transplantation as salvage therapy for pediatric primary CNS malignancies1178-2013https://doaj.org/article/fba72393f1934b7795a25aa9deb234c32014-07-01T00:00:00Zhttp://www.dovepress.com/dose-intensity-and-autologous-stem-cell-transplantation-as-salvage-the-a17489https://doaj.org/toc/1178-2013 Seiji Kojima,1 Andrei Cucuianu,2,3 Yoshiyuki Takahashi,1 Ioana Berindan-Neagoe,4–6 Ioan-Stefan Florian,7 Delia Dima,2 Ciprian Tomuleasa2,4 1Department of Paediatrics, Nagoya University Graduate School of Medicine, Nagoya, Japan; 2Department of Hematology, Ion Chiricuta Oncology Institute, Cluj Napoca, Romania; 3Department of Hematology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj Napoca, Romania; 4Department of Functional Genomics and Experimental Pathology, Ion Chiricuta Oncology Institute, Cluj Napoca, Romania; 5Department of Immunology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj Napoca, Romania; 6Research Center for Functional Genomics, Biomedicine and Translational Medicine, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj Napoca, Romania; 7Department of Neurosurgery, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj Napoca, RomaniaWe have read with great interest the work of Lu et al published recently in the International Journal of Nanomedicine,1 in which the authors describe different strategies for an efficient delivery of drugs to the central nervous system (CNS) across the blood–brain and blood–cerebrospinal fluid barriers. The paper describes in a very organized and efficient manner the current approaches to improve the penetration of various drugs across the blood–brain barrier, of key importance in CNS malignancies.Read the original paperKojima SCucuianu ATakahashi YBerindan-Neagoe IFlorian ISDima DTomuleasa CDove Medical PressarticleMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol 2014, Iss Issue 1, Pp 3247-3248 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine (General) R5-920
spellingShingle	Medicine (General) R5-920 Kojima S Cucuianu A Takahashi Y Berindan-Neagoe I Florian IS Dima D Tomuleasa C Dose intensity and autologous stem cell transplantation as salvage therapy for pediatric primary CNS malignancies
description	Seiji Kojima,1 Andrei Cucuianu,2,3 Yoshiyuki Takahashi,1 Ioana Berindan-Neagoe,4–6 Ioan-Stefan Florian,7 Delia Dima,2 Ciprian Tomuleasa2,4 1Department of Paediatrics, Nagoya University Graduate School of Medicine, Nagoya, Japan; 2Department of Hematology, Ion Chiricuta Oncology Institute, Cluj Napoca, Romania; 3Department of Hematology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj Napoca, Romania; 4Department of Functional Genomics and Experimental Pathology, Ion Chiricuta Oncology Institute, Cluj Napoca, Romania; 5Department of Immunology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj Napoca, Romania; 6Research Center for Functional Genomics, Biomedicine and Translational Medicine, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj Napoca, Romania; 7Department of Neurosurgery, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj Napoca, RomaniaWe have read with great interest the work of Lu et al published recently in the International Journal of Nanomedicine,1 in which the authors describe different strategies for an efficient delivery of drugs to the central nervous system (CNS) across the blood–brain and blood–cerebrospinal fluid barriers. The paper describes in a very organized and efficient manner the current approaches to improve the penetration of various drugs across the blood–brain barrier, of key importance in CNS malignancies.Read the original paper
format	article
author	Kojima S Cucuianu A Takahashi Y Berindan-Neagoe I Florian IS Dima D Tomuleasa C
author_facet	Kojima S Cucuianu A Takahashi Y Berindan-Neagoe I Florian IS Dima D Tomuleasa C
author_sort	Kojima S
title	Dose intensity and autologous stem cell transplantation as salvage therapy for pediatric primary CNS malignancies
title_short	Dose intensity and autologous stem cell transplantation as salvage therapy for pediatric primary CNS malignancies
title_full	Dose intensity and autologous stem cell transplantation as salvage therapy for pediatric primary CNS malignancies
title_fullStr	Dose intensity and autologous stem cell transplantation as salvage therapy for pediatric primary CNS malignancies
title_full_unstemmed	Dose intensity and autologous stem cell transplantation as salvage therapy for pediatric primary CNS malignancies
title_sort	dose intensity and autologous stem cell transplantation as salvage therapy for pediatric primary cns malignancies
publisher	Dove Medical Press
publishDate	2014
url	https://doaj.org/article/fba72393f1934b7795a25aa9deb234c3
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_version_	1718403593685434368

Dose intensity and autologous stem cell transplantation as salvage therapy for pediatric primary CNS malignancies

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