A non-canonical mismatch repair pathway in prokaryotes
Despite the importance of mismatch repair for genome stability, many Archaea and almost all Actinobacteria lack MutS and MutL proteins. Here the authors, usingMycobacterium smegmatisas a model, report that NucS/EndoMS endonuclease acts in a distinct mismatch repair pathway.
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Nature Portfolio
2017
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oai:doaj.org-article:fbb1cf5e25104952a827c5274205d0f72021-12-02T14:40:35ZA non-canonical mismatch repair pathway in prokaryotes10.1038/ncomms142462041-1723https://doaj.org/article/fbb1cf5e25104952a827c5274205d0f72017-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms14246https://doaj.org/toc/2041-1723Despite the importance of mismatch repair for genome stability, many Archaea and almost all Actinobacteria lack MutS and MutL proteins. Here the authors, usingMycobacterium smegmatisas a model, report that NucS/EndoMS endonuclease acts in a distinct mismatch repair pathway.A. Castañeda-GarcíaA. I. PrietoJ. Rodríguez-BeltránN. AlonsoD. CantillonC. CostasL. Pérez-LagoE. D. ZegeyeM. HerranzP. PlocińskiT. TonjumD. García de ViedmaM. PagetS. J. WaddellA. M. RojasA. J. DohertyJ. BlázquezNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-10 (2017) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q A. Castañeda-García A. I. Prieto J. Rodríguez-Beltrán N. Alonso D. Cantillon C. Costas L. Pérez-Lago E. D. Zegeye M. Herranz P. Plociński T. Tonjum D. García de Viedma M. Paget S. J. Waddell A. M. Rojas A. J. Doherty J. Blázquez A non-canonical mismatch repair pathway in prokaryotes |
| description |
Despite the importance of mismatch repair for genome stability, many Archaea and almost all Actinobacteria lack MutS and MutL proteins. Here the authors, usingMycobacterium smegmatisas a model, report that NucS/EndoMS endonuclease acts in a distinct mismatch repair pathway. |
| format |
article |
| author |
A. Castañeda-García A. I. Prieto J. Rodríguez-Beltrán N. Alonso D. Cantillon C. Costas L. Pérez-Lago E. D. Zegeye M. Herranz P. Plociński T. Tonjum D. García de Viedma M. Paget S. J. Waddell A. M. Rojas A. J. Doherty J. Blázquez |
| author_facet |
A. Castañeda-García A. I. Prieto J. Rodríguez-Beltrán N. Alonso D. Cantillon C. Costas L. Pérez-Lago E. D. Zegeye M. Herranz P. Plociński T. Tonjum D. García de Viedma M. Paget S. J. Waddell A. M. Rojas A. J. Doherty J. Blázquez |
| author_sort |
A. Castañeda-García |
| title |
A non-canonical mismatch repair pathway in prokaryotes |
| title_short |
A non-canonical mismatch repair pathway in prokaryotes |
| title_full |
A non-canonical mismatch repair pathway in prokaryotes |
| title_fullStr |
A non-canonical mismatch repair pathway in prokaryotes |
| title_full_unstemmed |
A non-canonical mismatch repair pathway in prokaryotes |
| title_sort |
non-canonical mismatch repair pathway in prokaryotes |
| publisher |
Nature Portfolio |
| publishDate |
2017 |
| url |
https://doaj.org/article/fbb1cf5e25104952a827c5274205d0f7 |
| work_keys_str_mv |
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