A Long-Term Follow-Up of Dental and Craniofacial Disturbances after Cancer Therapy in a Pediatric Rhabdomyosarcoma Patient: Case Report

Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children and adolescents. A boy aged seven years and five months was diagnosed with stage three group III embryonal parameningeal RMS with intracranial extension. He received chemotherapy for 23 weeks in combination with localized radi...

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Autores principales:	Pei-Ching Chang, Shiao-Yu Lin
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	dental disturbance craniofacial disturbance chemoradiation therapy rhabdomyosarcoma Medicine R
Acceso en línea:	https://doaj.org/article/fbb9ffed3dfb4bbc8e21127ee4f9ba9c
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spelling	oai:doaj.org-article:fbb9ffed3dfb4bbc8e21127ee4f9ba9c2021-11-25T17:51:40ZA Long-Term Follow-Up of Dental and Craniofacial Disturbances after Cancer Therapy in a Pediatric Rhabdomyosarcoma Patient: Case Report10.3390/ijerph1822121581660-46011661-7827https://doaj.org/article/fbb9ffed3dfb4bbc8e21127ee4f9ba9c2021-11-01T00:00:00Zhttps://www.mdpi.com/1660-4601/18/22/12158https://doaj.org/toc/1661-7827https://doaj.org/toc/1660-4601Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children and adolescents. A boy aged seven years and five months was diagnosed with stage three group III embryonal parameningeal RMS with intracranial extension. He received chemotherapy for 23 weeks in combination with localized radiotherapy during the inductive phase of nine weeks (a total tumor dose of 5040 cGy). Three months later, he was referred to the department of pediatric dentistry for radiation-induced caries, the treatment of which was later terminated because of severe trismus and radiation-induced oropharyngeal mucositis. Three years later, the patient returned for the fitting of a prosthesis because of mastication problems. The dental treatments performed included: extraction, banding, composite resin restorations, root canal fillings, and stainless steel crown fabrication. An interim denture was fitted due to the poor retention of the fixed prosthesis. As the patient grew older, they developed facial asymmetry as a result of the prominent atrophy of their right cheek. By the age of 32, they had lost multiple teeth and exhibited severe facial deformity. Therefore, it is essential not only to involve a multidisciplinary medical team before, during, and after cancer therapy, but also to initiate long-term follow-ups given the potential effects of late sequelae after chemoradiation in multiple developmental areas.Pei-Ching ChangShiao-Yu LinMDPI AGarticledental disturbancecraniofacial disturbancechemoradiation therapyrhabdomyosarcomaMedicineRENInternational Journal of Environmental Research and Public Health, Vol 18, Iss 12158, p 12158 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	dental disturbance craniofacial disturbance chemoradiation therapy rhabdomyosarcoma Medicine R
spellingShingle	dental disturbance craniofacial disturbance chemoradiation therapy rhabdomyosarcoma Medicine R Pei-Ching Chang Shiao-Yu Lin A Long-Term Follow-Up of Dental and Craniofacial Disturbances after Cancer Therapy in a Pediatric Rhabdomyosarcoma Patient: Case Report
description	Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children and adolescents. A boy aged seven years and five months was diagnosed with stage three group III embryonal parameningeal RMS with intracranial extension. He received chemotherapy for 23 weeks in combination with localized radiotherapy during the inductive phase of nine weeks (a total tumor dose of 5040 cGy). Three months later, he was referred to the department of pediatric dentistry for radiation-induced caries, the treatment of which was later terminated because of severe trismus and radiation-induced oropharyngeal mucositis. Three years later, the patient returned for the fitting of a prosthesis because of mastication problems. The dental treatments performed included: extraction, banding, composite resin restorations, root canal fillings, and stainless steel crown fabrication. An interim denture was fitted due to the poor retention of the fixed prosthesis. As the patient grew older, they developed facial asymmetry as a result of the prominent atrophy of their right cheek. By the age of 32, they had lost multiple teeth and exhibited severe facial deformity. Therefore, it is essential not only to involve a multidisciplinary medical team before, during, and after cancer therapy, but also to initiate long-term follow-ups given the potential effects of late sequelae after chemoradiation in multiple developmental areas.
format	article
author	Pei-Ching Chang Shiao-Yu Lin
author_facet	Pei-Ching Chang Shiao-Yu Lin
author_sort	Pei-Ching Chang
title	A Long-Term Follow-Up of Dental and Craniofacial Disturbances after Cancer Therapy in a Pediatric Rhabdomyosarcoma Patient: Case Report
title_short	A Long-Term Follow-Up of Dental and Craniofacial Disturbances after Cancer Therapy in a Pediatric Rhabdomyosarcoma Patient: Case Report
title_full	A Long-Term Follow-Up of Dental and Craniofacial Disturbances after Cancer Therapy in a Pediatric Rhabdomyosarcoma Patient: Case Report
title_fullStr	A Long-Term Follow-Up of Dental and Craniofacial Disturbances after Cancer Therapy in a Pediatric Rhabdomyosarcoma Patient: Case Report
title_full_unstemmed	A Long-Term Follow-Up of Dental and Craniofacial Disturbances after Cancer Therapy in a Pediatric Rhabdomyosarcoma Patient: Case Report
title_sort	long-term follow-up of dental and craniofacial disturbances after cancer therapy in a pediatric rhabdomyosarcoma patient: case report
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/fbb9ffed3dfb4bbc8e21127ee4f9ba9c
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A Long-Term Follow-Up of Dental and Craniofacial Disturbances after Cancer Therapy in a Pediatric Rhabdomyosarcoma Patient: Case Report

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