Mechanism of NanR gene repression and allosteric induction of bacterial sialic acid metabolism

The GntR superfamily is one of the largest families of transcription factors in prokaryotes. Here the authors combine biophysical analysis and structural biology to dissect the mechanism by which NanR — a GntR-family regulator — binds to its promoter to repress the transcription of genes necessary f...

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Autores principales: Christopher R. Horne, Hariprasad Venugopal, Santosh Panjikar, David M. Wood, Amy Henrickson, Emre Brookes, Rachel A. North, James M. Murphy, Rosmarie Friemann, Michael D. W. Griffin, Georg Ramm, Borries Demeler, Renwick C. J. Dobson
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/fbbaf67cd57e43b9861716dfe16d3c75
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