Sequential dual-drug delivery of BMP-2 and alendronate from hydroxyapatite-collagen scaffolds for enhanced bone regeneration
Abstract The clinical use of bioactive molecules in bone regeneration has been known to have side effects, which result from uncontrolled and supraphysiological doses. In this study, we demonstrated the synergistic effect of two bioactive molecules, bone morphogenic protein-2 (BMP-2) and alendronate...
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Auteurs principaux: | Dongtak Lee, Maierdanjiang Wufuer, Insu Kim, Tae Hyun Choi, Byung Jun Kim, Hyo Gi Jung, Byoungjun Jeon, Gyudo Lee, Ok Hee Jeon, Hak Chang, Dae Sung Yoon |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2021
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Accès en ligne: | https://doaj.org/article/fbcb851d97a242b7bc43e09f893dc079 |
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