A four-gene signature predicts survival and anti-CTLA4 immunotherapeutic responses based on immune classification of melanoma

Ying Mei et al. identify a four-gene tumor immune-relevant signature that predicts the overall survival of melanoma patients and their response to the CTLA4 antibody ipilimumab. This study suggests a potential utility of this four-gene signature in prognosis, risk assessment, and prediction of anti-...

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Autores principales: Ying Mei, Mei-Ju May Chen, Han Liang, Li Ma
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/fbcc56ff9b0345b58cd3dc909e49d8e4
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spelling oai:doaj.org-article:fbcc56ff9b0345b58cd3dc909e49d8e42021-12-02T13:24:24ZA four-gene signature predicts survival and anti-CTLA4 immunotherapeutic responses based on immune classification of melanoma10.1038/s42003-021-01911-x2399-3642https://doaj.org/article/fbcc56ff9b0345b58cd3dc909e49d8e42021-03-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-01911-xhttps://doaj.org/toc/2399-3642Ying Mei et al. identify a four-gene tumor immune-relevant signature that predicts the overall survival of melanoma patients and their response to the CTLA4 antibody ipilimumab. This study suggests a potential utility of this four-gene signature in prognosis, risk assessment, and prediction of anti-CTLA4 response in melanoma patients.Ying MeiMei-Ju May ChenHan LiangLi MaNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Ying Mei
Mei-Ju May Chen
Han Liang
Li Ma
A four-gene signature predicts survival and anti-CTLA4 immunotherapeutic responses based on immune classification of melanoma
description Ying Mei et al. identify a four-gene tumor immune-relevant signature that predicts the overall survival of melanoma patients and their response to the CTLA4 antibody ipilimumab. This study suggests a potential utility of this four-gene signature in prognosis, risk assessment, and prediction of anti-CTLA4 response in melanoma patients.
format article
author Ying Mei
Mei-Ju May Chen
Han Liang
Li Ma
author_facet Ying Mei
Mei-Ju May Chen
Han Liang
Li Ma
author_sort Ying Mei
title A four-gene signature predicts survival and anti-CTLA4 immunotherapeutic responses based on immune classification of melanoma
title_short A four-gene signature predicts survival and anti-CTLA4 immunotherapeutic responses based on immune classification of melanoma
title_full A four-gene signature predicts survival and anti-CTLA4 immunotherapeutic responses based on immune classification of melanoma
title_fullStr A four-gene signature predicts survival and anti-CTLA4 immunotherapeutic responses based on immune classification of melanoma
title_full_unstemmed A four-gene signature predicts survival and anti-CTLA4 immunotherapeutic responses based on immune classification of melanoma
title_sort four-gene signature predicts survival and anti-ctla4 immunotherapeutic responses based on immune classification of melanoma
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/fbcc56ff9b0345b58cd3dc909e49d8e4
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