NLRP3 phosphorylation in its LRR domain critically regulates inflammasome assembly

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NLRP3 phosphorylation in its LRR domain critically regulates inflammasome assembly

Nlrp3 inflammasome activation requires Nek7 recruitment to drive ASC speck formation. Here the authors show how Nlrp3 phosphorylation events control this Nek7 recruitment.

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Detalles Bibliográficos
Autores principales:	Tingting Niu, Charlotte De Rosny, Séverine Chautard, Amaury Rey, Danish Patoli, Marine Groslambert, Camille Cosson, Brice Lagrange, Zhirong Zhang, Orane Visvikis, Sabine Hacot, Maggy Hologne, Olivier Walker, Jeimin Wong, Ping Wang, Roméo Ricci, Thomas Henry, Laurent Boyer, Virginie Petrilli, Bénédicte F. Py
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/fbcf468393234f91b37ce912376f58ab
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

Internet

https://doaj.org/article/fbcf468393234f91b37ce912376f58ab