ANTICOAGULATION CONTROL AMONG PATIENTS WITH ATRIAL FIBRILLATION

Objective: To assess adequacy of anticoagulation in Warfarin treated patients with atrial fibrillation Study Design: Prospective observational study. Place and Duration of Study: Armed Forces Institute of Cardiology/National Institute of Heart Diseases, Rawalpindi, from Nov 2019 to Apr 2020....

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Autores principales: Amer Rauf, Azmat Hayat, Noor Shah, Kumail Abbas, Waqas Khalid, Sayed Tanveer Abbas Gilani
Formato: article
Lenguaje:EN
Publicado: Army Medical College Rawalpindi 2020
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spelling oai:doaj.org-article:fbef6e22318f43909826da2352610f2b2021-12-02T19:11:08ZANTICOAGULATION CONTROL AMONG PATIENTS WITH ATRIAL FIBRILLATIONdoi.org/10.51253/pafmj.v70iSuppl-4.60210030-96482411-8842https://doaj.org/article/fbef6e22318f43909826da2352610f2b2020-12-01T00:00:00Zhttps://pafmj.org/index.php/PAFMJ/article/view/6021https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To assess adequacy of anticoagulation in Warfarin treated patients with atrial fibrillation Study Design: Prospective observational study. Place and Duration of Study: Armed Forces Institute of Cardiology/National Institute of Heart Diseases, Rawalpindi, from Nov 2019 to Apr 2020. Methodology: All individuals fulfilling the inclusion criteria were enrolled in the study after their consent. Based upon their serial International Normalized Ratio (INR) values, Time in Therapeutic Range (TTR) was calculated using Rosendaal method. A TTR>70% was a marker of adequate anticoagulation. Factors associated with TTR <70% were identified. Results: Total 70 participants were included in the study. Mean age (± SD) was 51.43 (± 11.27) years. Thirty four (48.6%) were males and 36 (51.4%) were females. Twenty four (34.3%) had valvular atrial fibrillation while 46 (65.7%) had non-valvular atrial fibrillation. Overall, TTR>70% was observed in 29 (41.4%) of study participants. Poly-pharmacy and multiple co-morbidities were identified as statistically significant factors associated with subtherapeutic anticoagulation (TTR<70%). Conclusion: Determined TTR of study population indicates poor anticoagulation control in majority of patients being anticoagulated with Warfar in highlighting the need for focused interventions such as dedicated anticoagulation clinics and patient education.Amer RaufAzmat HayatNoor ShahKumail AbbasWaqas KhalidSayed Tanveer Abbas GilaniArmy Medical College Rawalpindiarticleanticoagulantsatrial fibrillationwarfarinMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 70, Iss 4, Pp 768-771 (2020)
institution DOAJ
collection DOAJ
language EN
topic anticoagulants
atrial fibrillation
warfarin
Medicine
R
Medicine (General)
R5-920
spellingShingle anticoagulants
atrial fibrillation
warfarin
Medicine
R
Medicine (General)
R5-920
Amer Rauf
Azmat Hayat
Noor Shah
Kumail Abbas
Waqas Khalid
Sayed Tanveer Abbas Gilani
ANTICOAGULATION CONTROL AMONG PATIENTS WITH ATRIAL FIBRILLATION
description Objective: To assess adequacy of anticoagulation in Warfarin treated patients with atrial fibrillation Study Design: Prospective observational study. Place and Duration of Study: Armed Forces Institute of Cardiology/National Institute of Heart Diseases, Rawalpindi, from Nov 2019 to Apr 2020. Methodology: All individuals fulfilling the inclusion criteria were enrolled in the study after their consent. Based upon their serial International Normalized Ratio (INR) values, Time in Therapeutic Range (TTR) was calculated using Rosendaal method. A TTR>70% was a marker of adequate anticoagulation. Factors associated with TTR <70% were identified. Results: Total 70 participants were included in the study. Mean age (± SD) was 51.43 (± 11.27) years. Thirty four (48.6%) were males and 36 (51.4%) were females. Twenty four (34.3%) had valvular atrial fibrillation while 46 (65.7%) had non-valvular atrial fibrillation. Overall, TTR>70% was observed in 29 (41.4%) of study participants. Poly-pharmacy and multiple co-morbidities were identified as statistically significant factors associated with subtherapeutic anticoagulation (TTR<70%). Conclusion: Determined TTR of study population indicates poor anticoagulation control in majority of patients being anticoagulated with Warfar in highlighting the need for focused interventions such as dedicated anticoagulation clinics and patient education.
format article
author Amer Rauf
Azmat Hayat
Noor Shah
Kumail Abbas
Waqas Khalid
Sayed Tanveer Abbas Gilani
author_facet Amer Rauf
Azmat Hayat
Noor Shah
Kumail Abbas
Waqas Khalid
Sayed Tanveer Abbas Gilani
author_sort Amer Rauf
title ANTICOAGULATION CONTROL AMONG PATIENTS WITH ATRIAL FIBRILLATION
title_short ANTICOAGULATION CONTROL AMONG PATIENTS WITH ATRIAL FIBRILLATION
title_full ANTICOAGULATION CONTROL AMONG PATIENTS WITH ATRIAL FIBRILLATION
title_fullStr ANTICOAGULATION CONTROL AMONG PATIENTS WITH ATRIAL FIBRILLATION
title_full_unstemmed ANTICOAGULATION CONTROL AMONG PATIENTS WITH ATRIAL FIBRILLATION
title_sort anticoagulation control among patients with atrial fibrillation
publisher Army Medical College Rawalpindi
publishDate 2020
url https://doaj.org/article/fbef6e22318f43909826da2352610f2b
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AT noorshah anticoagulationcontrolamongpatientswithatrialfibrillation
AT kumailabbas anticoagulationcontrolamongpatientswithatrialfibrillation
AT waqaskhalid anticoagulationcontrolamongpatientswithatrialfibrillation
AT sayedtanveerabbasgilani anticoagulationcontrolamongpatientswithatrialfibrillation
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