A tumour-selective cascade activatable self-detained system for drug delivery and cancer imaging

A tumour-selective cascade activatable self-detained system for drug delivery and cancer imaging

The activation of drugs within cellular systems may provide targeted therapies for cancer. Here, the authors make a drug delivery system that is activated within the cell and exploits XIAP expression to cleave a linker region, resulting in the self-assembly of the system and drug release within canc...

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Autores principales: Hong-Wei An, Li-Li Li, Yi Wang, Ziqi Wang, Dayong Hou, Yao-Xin Lin, Sheng-Lin Qiao, Man-Di Wang, Chao Yang, Yong Cong, Yang Ma, Xiao-Xiao Zhao, Qian Cai, Wen-Ting Chen, Chu-Qi Lu, Wanhai Xu, Hao Wang, Yuliang Zhao
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Science
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Acceso en línea:https://doaj.org/article/fbf5c28ff08842509d74e20473d50db1
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