Linking of primary care records to census data to study the association between socioeconomic status and cancer incidence in Southern Europe: a nation-wide ecological study.

<h4>Background</h4>Area-based measures of economic deprivation are seldom applied to large medical records databases to establish population-scale associations between deprivation and disease.<h4>Objective</h4>To study the association between deprivation and incidence of comm...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Maria Garcia-Gil, Josep-Maria Elorza, Marta Banque, Marc Comas-Cufí, Jordi Blanch, Rafel Ramos, Leonardo Méndez-Boo, Eduardo Hermosilla, Bonaventura Bolibar, Daniel Prieto-Alhambra
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2014
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/fbf9d19bd7a043b0a490f533a0db2366
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:fbf9d19bd7a043b0a490f533a0db2366
record_format	dspace
spelling	oai:doaj.org-article:fbf9d19bd7a043b0a490f533a0db23662021-11-25T05:55:57ZLinking of primary care records to census data to study the association between socioeconomic status and cancer incidence in Southern Europe: a nation-wide ecological study.1932-620310.1371/journal.pone.0109706https://doaj.org/article/fbf9d19bd7a043b0a490f533a0db23662014-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0109706https://doaj.org/toc/1932-6203<h4>Background</h4>Area-based measures of economic deprivation are seldom applied to large medical records databases to establish population-scale associations between deprivation and disease.<h4>Objective</h4>To study the association between deprivation and incidence of common cancer types in a Southern European region.<h4>Methods</h4>Retrospective ecological study using the SIDIAP (Information System for the Development of Research in Primary Care) database of longitudinal electronic medical records for a representative population of Catalonia (Spain) and the MEDEA index based on urban socioeconomic indicators in the Spanish census. Study outcomes were incident cervical, breast, colorectal, prostate, and lung cancer in 2009-2012. The completeness of SIDIAP cancer recording was evaluated through linkage of a geographic data subset to a hospital cancer registry. Associations between MEDEA quintiles and cancer incidence was evaluated using zero-inflated Poisson regression adjusted for sex, age, smoking, alcoholism, obesity, hypertension, and diabetes.<h4>Results</h4>SIDIAP sensitivity was 63% to 92% for the five cancers studied. There was direct association between deprivation and lung, colorectal, and cervical cancer: incidence rate ratios (IRR) 1.82 [1.64-2.01], IRR 1.60 [1.34-1.90], IRR 1.22 [1.07-1.38], respectively, comparing the most deprived to most affluent areas. In wealthy areas, prostate and breast cancers were more common: IRR 0.92 [0.80-1.00], IRR 0.91 [0.78-1.06]. Adjustment for confounders attenuated the association with lung cancer risk (fully adjusted IRR 1.16 [1.08-1.25]), reversed the direction of the association with colorectal cancer (IRR 0.90 [0.84-0.95]), and did not modify the associations with cervical (IRR 1.27 [1.11-1.45]), prostate (0.74 [0.69-0.80]), and breast (0.76 [0.71-0.81]) cancer.<h4>Conclusions</h4>Deprivation is associated differently with the occurrence of various cancer types. These results provide evidence that MEDEA is a useful, area-based deprivation index for analyses of the SIDIAP database. This information will be useful to improve screening programs, cancer prevention and management strategies, to reach patients more effectively, particularly in deprived urban areas.Maria Garcia-GilJosep-Maria ElorzaMarta BanqueMarc Comas-CufíJordi BlanchRafel RamosLeonardo Méndez-BooEduardo HermosillaBonaventura BolibarDaniel Prieto-AlhambraPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 9, Iss 10, p e109706 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Maria Garcia-Gil Josep-Maria Elorza Marta Banque Marc Comas-Cufí Jordi Blanch Rafel Ramos Leonardo Méndez-Boo Eduardo Hermosilla Bonaventura Bolibar Daniel Prieto-Alhambra Linking of primary care records to census data to study the association between socioeconomic status and cancer incidence in Southern Europe: a nation-wide ecological study.
description	<h4>Background</h4>Area-based measures of economic deprivation are seldom applied to large medical records databases to establish population-scale associations between deprivation and disease.<h4>Objective</h4>To study the association between deprivation and incidence of common cancer types in a Southern European region.<h4>Methods</h4>Retrospective ecological study using the SIDIAP (Information System for the Development of Research in Primary Care) database of longitudinal electronic medical records for a representative population of Catalonia (Spain) and the MEDEA index based on urban socioeconomic indicators in the Spanish census. Study outcomes were incident cervical, breast, colorectal, prostate, and lung cancer in 2009-2012. The completeness of SIDIAP cancer recording was evaluated through linkage of a geographic data subset to a hospital cancer registry. Associations between MEDEA quintiles and cancer incidence was evaluated using zero-inflated Poisson regression adjusted for sex, age, smoking, alcoholism, obesity, hypertension, and diabetes.<h4>Results</h4>SIDIAP sensitivity was 63% to 92% for the five cancers studied. There was direct association between deprivation and lung, colorectal, and cervical cancer: incidence rate ratios (IRR) 1.82 [1.64-2.01], IRR 1.60 [1.34-1.90], IRR 1.22 [1.07-1.38], respectively, comparing the most deprived to most affluent areas. In wealthy areas, prostate and breast cancers were more common: IRR 0.92 [0.80-1.00], IRR 0.91 [0.78-1.06]. Adjustment for confounders attenuated the association with lung cancer risk (fully adjusted IRR 1.16 [1.08-1.25]), reversed the direction of the association with colorectal cancer (IRR 0.90 [0.84-0.95]), and did not modify the associations with cervical (IRR 1.27 [1.11-1.45]), prostate (0.74 [0.69-0.80]), and breast (0.76 [0.71-0.81]) cancer.<h4>Conclusions</h4>Deprivation is associated differently with the occurrence of various cancer types. These results provide evidence that MEDEA is a useful, area-based deprivation index for analyses of the SIDIAP database. This information will be useful to improve screening programs, cancer prevention and management strategies, to reach patients more effectively, particularly in deprived urban areas.
format	article
author	Maria Garcia-Gil Josep-Maria Elorza Marta Banque Marc Comas-Cufí Jordi Blanch Rafel Ramos Leonardo Méndez-Boo Eduardo Hermosilla Bonaventura Bolibar Daniel Prieto-Alhambra
author_facet	Maria Garcia-Gil Josep-Maria Elorza Marta Banque Marc Comas-Cufí Jordi Blanch Rafel Ramos Leonardo Méndez-Boo Eduardo Hermosilla Bonaventura Bolibar Daniel Prieto-Alhambra
author_sort	Maria Garcia-Gil
title	Linking of primary care records to census data to study the association between socioeconomic status and cancer incidence in Southern Europe: a nation-wide ecological study.
title_short	Linking of primary care records to census data to study the association between socioeconomic status and cancer incidence in Southern Europe: a nation-wide ecological study.
title_full	Linking of primary care records to census data to study the association between socioeconomic status and cancer incidence in Southern Europe: a nation-wide ecological study.
title_fullStr	Linking of primary care records to census data to study the association between socioeconomic status and cancer incidence in Southern Europe: a nation-wide ecological study.
title_full_unstemmed	Linking of primary care records to census data to study the association between socioeconomic status and cancer incidence in Southern Europe: a nation-wide ecological study.
title_sort	linking of primary care records to census data to study the association between socioeconomic status and cancer incidence in southern europe: a nation-wide ecological study.
publisher	Public Library of Science (PLoS)
publishDate	2014
url	https://doaj.org/article/fbf9d19bd7a043b0a490f533a0db2366
work_keys_str_mv	AT mariagarciagil linkingofprimarycarerecordstocensusdatatostudytheassociationbetweensocioeconomicstatusandcancerincidenceinsoutherneuropeanationwideecologicalstudy AT josepmariaelorza linkingofprimarycarerecordstocensusdatatostudytheassociationbetweensocioeconomicstatusandcancerincidenceinsoutherneuropeanationwideecologicalstudy AT martabanque linkingofprimarycarerecordstocensusdatatostudytheassociationbetweensocioeconomicstatusandcancerincidenceinsoutherneuropeanationwideecologicalstudy AT marccomascufi linkingofprimarycarerecordstocensusdatatostudytheassociationbetweensocioeconomicstatusandcancerincidenceinsoutherneuropeanationwideecologicalstudy AT jordiblanch linkingofprimarycarerecordstocensusdatatostudytheassociationbetweensocioeconomicstatusandcancerincidenceinsoutherneuropeanationwideecologicalstudy AT rafelramos linkingofprimarycarerecordstocensusdatatostudytheassociationbetweensocioeconomicstatusandcancerincidenceinsoutherneuropeanationwideecologicalstudy AT leonardomendezboo linkingofprimarycarerecordstocensusdatatostudytheassociationbetweensocioeconomicstatusandcancerincidenceinsoutherneuropeanationwideecologicalstudy AT eduardohermosilla linkingofprimarycarerecordstocensusdatatostudytheassociationbetweensocioeconomicstatusandcancerincidenceinsoutherneuropeanationwideecologicalstudy AT bonaventurabolibar linkingofprimarycarerecordstocensusdatatostudytheassociationbetweensocioeconomicstatusandcancerincidenceinsoutherneuropeanationwideecologicalstudy AT danielprietoalhambra linkingofprimarycarerecordstocensusdatatostudytheassociationbetweensocioeconomicstatusandcancerincidenceinsoutherneuropeanationwideecologicalstudy
_version_	1718414379284692992

Linking of primary care records to census data to study the association between socioeconomic status and cancer incidence in Southern Europe: a nation-wide ecological study.

Ejemplares similares