Multifunctional Coating with Both Thermal Insulation and Antibacterial Properties Applied to Nickel-Titanium Alloy

ZhiBo Liu,* KangWen Xiao,* ZhiQiang Hou, FeiFei Yan, Yan Chen, Lin Cai Department of Orthopedics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei 430071, People’s Republic of China*These authors contributed equally to this workCorrespondence: Lin Cai Tel +86 1388609 6467Email orthopedi...

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Autores principales:	Liu Z, Xiao K, Hou Z, Yan F, Chen Y, Cai L
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2020
Materias:	ermal insulation nickel-titanium alloy silver nanoparticles micro-arc oxidation Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/fbfa682584f94d948230dc3bde30d99a
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spelling	oai:doaj.org-article:fbfa682584f94d948230dc3bde30d99a2021-12-02T08:09:56ZMultifunctional Coating with Both Thermal Insulation and Antibacterial Properties Applied to Nickel-Titanium Alloy1178-2013https://doaj.org/article/fbfa682584f94d948230dc3bde30d99a2020-09-01T00:00:00Zhttps://www.dovepress.com/multifunctional-coating-with-both-thermal-insulation-and-antibacterial-peer-reviewed-article-IJNhttps://doaj.org/toc/1178-2013ZhiBo Liu,* KangWen Xiao,* ZhiQiang Hou, FeiFei Yan, Yan Chen, Lin Cai Department of Orthopedics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei 430071, People’s Republic of China*These authors contributed equally to this workCorrespondence: Lin Cai Tel +86 1388609 6467Email orthopedics@whu.edu.cnBackground: With excellent shape memory and superelastic properties, shape memory alloy (SMA) is an ideal actuator, and it can form smart structure for different applications in medical field. However, SMA devices cause apparent thermal damage to the surrounding tissues when it works in vivo, making the application of smart structure that is composed of SMA actuator in vivo is greatly limited.Methods: In this paper, coating (APA) with PLA as the main body to limit the heat conduction, a multifunctional Ag nanoparticles (AgNPs)/polylactic acid (PLA)/Al2O3 was synthesized. The Al2O3 layer was formed by micro-arc oxidation (MAO) and AgNPs were synthesized by silver nitrate and ethylene glycol. Scanning electron microscopy, transmission electron microscope, and Fourier transform infrared spectra were applied to analyze the morphology and characterization of APA coating. The antimicrobial activity, thermal insulation activity, and biocompatibility of APA coating were furtherly explored and verified through animal experiments and immunohistochemistry.Results: With different particle sizes and concentrations of AgNPs, APA multi-functional films were successfully prepared. The Al2O3 layer was closely combined with SMA and formed a porous surface, so the PLA and AgNPs layers can firmly adhere to SMA, thus reducing the release of nickel ions in SMA. AgNPs gave APA coating excellent antibacterial activity and effectively inhibited the growth of Staphylococcus aureus. In addition, coupled with the low thermal conductivity of PLA and Al2O3, AgNPs were tightly anchored on the surface of PLA, which has high infrared reflectivity, making the APA coating obtain good thermal insulation performance.Conclusion: We have successfully prepared the APA coating and obtained the optimum amount of AgNPs, which makes it have good thermal insulation performance, good antibacterial activity and good biocompatibility, which provides a new prospect for the application of SMA.Keywords: thermal insulation, nickel-titanium alloy, silver nanoparticles, micro-arc oxidationLiu ZXiao KHou ZYan FChen YCai LDove Medical Pressarticleermal insulationnickel-titanium alloysilver nanoparticlesmicro-arc oxidationMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol Volume 15, Pp 7215-7234 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	ermal insulation nickel-titanium alloy silver nanoparticles micro-arc oxidation Medicine (General) R5-920
spellingShingle	ermal insulation nickel-titanium alloy silver nanoparticles micro-arc oxidation Medicine (General) R5-920 Liu Z Xiao K Hou Z Yan F Chen Y Cai L Multifunctional Coating with Both Thermal Insulation and Antibacterial Properties Applied to Nickel-Titanium Alloy
description	ZhiBo Liu,* KangWen Xiao,* ZhiQiang Hou, FeiFei Yan, Yan Chen, Lin Cai Department of Orthopedics, Zhongnan Hospital of Wuhan University, Wuhan, Hubei 430071, People’s Republic of China*These authors contributed equally to this workCorrespondence: Lin Cai Tel +86 1388609 6467Email orthopedics@whu.edu.cnBackground: With excellent shape memory and superelastic properties, shape memory alloy (SMA) is an ideal actuator, and it can form smart structure for different applications in medical field. However, SMA devices cause apparent thermal damage to the surrounding tissues when it works in vivo, making the application of smart structure that is composed of SMA actuator in vivo is greatly limited.Methods: In this paper, coating (APA) with PLA as the main body to limit the heat conduction, a multifunctional Ag nanoparticles (AgNPs)/polylactic acid (PLA)/Al2O3 was synthesized. The Al2O3 layer was formed by micro-arc oxidation (MAO) and AgNPs were synthesized by silver nitrate and ethylene glycol. Scanning electron microscopy, transmission electron microscope, and Fourier transform infrared spectra were applied to analyze the morphology and characterization of APA coating. The antimicrobial activity, thermal insulation activity, and biocompatibility of APA coating were furtherly explored and verified through animal experiments and immunohistochemistry.Results: With different particle sizes and concentrations of AgNPs, APA multi-functional films were successfully prepared. The Al2O3 layer was closely combined with SMA and formed a porous surface, so the PLA and AgNPs layers can firmly adhere to SMA, thus reducing the release of nickel ions in SMA. AgNPs gave APA coating excellent antibacterial activity and effectively inhibited the growth of Staphylococcus aureus. In addition, coupled with the low thermal conductivity of PLA and Al2O3, AgNPs were tightly anchored on the surface of PLA, which has high infrared reflectivity, making the APA coating obtain good thermal insulation performance.Conclusion: We have successfully prepared the APA coating and obtained the optimum amount of AgNPs, which makes it have good thermal insulation performance, good antibacterial activity and good biocompatibility, which provides a new prospect for the application of SMA.Keywords: thermal insulation, nickel-titanium alloy, silver nanoparticles, micro-arc oxidation
format	article
author	Liu Z Xiao K Hou Z Yan F Chen Y Cai L
author_facet	Liu Z Xiao K Hou Z Yan F Chen Y Cai L
author_sort	Liu Z
title	Multifunctional Coating with Both Thermal Insulation and Antibacterial Properties Applied to Nickel-Titanium Alloy
title_short	Multifunctional Coating with Both Thermal Insulation and Antibacterial Properties Applied to Nickel-Titanium Alloy
title_full	Multifunctional Coating with Both Thermal Insulation and Antibacterial Properties Applied to Nickel-Titanium Alloy
title_fullStr	Multifunctional Coating with Both Thermal Insulation and Antibacterial Properties Applied to Nickel-Titanium Alloy
title_full_unstemmed	Multifunctional Coating with Both Thermal Insulation and Antibacterial Properties Applied to Nickel-Titanium Alloy
title_sort	multifunctional coating with both thermal insulation and antibacterial properties applied to nickel-titanium alloy
publisher	Dove Medical Press
publishDate	2020
url	https://doaj.org/article/fbfa682584f94d948230dc3bde30d99a
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Multifunctional Coating with Both Thermal Insulation and Antibacterial Properties Applied to Nickel-Titanium Alloy

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