Conformational manipulation of scale-up prepared single-chain polymeric nanogels for multiscale regulation of cells

Cyclized or folded single-chain polymeric nano-objects are generally produced with low efficiency. Here, the authors have scaled up the preparation of supramolecular single-chain nanogels by RAFT polymerizations and applied the dynamic supramolecular single-chain nanogels to regulate cell behaviours...

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Autores principales: Xiaoyu Chen, Rui Li, Siu Hong Dexter Wong, Kongchang Wei, Miao Cui, Huaijun Chen, Yuanzhang Jiang, Boguang Yang, Pengchao Zhao, Jianbin Xu, Heng Chen, Chao Yin, Sien Lin, Wayne Yuk-Wai Lee, Yihan Jing, Zhen Li, Zhengmeng Yang, Jiang Xia, Guosong Chen, Gang Li, Liming Bian
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/fc18efe80f8c495f8372f5c738cdf7d7
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Sumario:Cyclized or folded single-chain polymeric nano-objects are generally produced with low efficiency. Here, the authors have scaled up the preparation of supramolecular single-chain nanogels by RAFT polymerizations and applied the dynamic supramolecular single-chain nanogels to regulate cell behaviours at varying scales.