Exosomes derived from palmitic acid-treated hepatocytes induce fibrotic activation of hepatic stellate cells
Abstract Non-alcoholic fatty liver disease (NAFLD) is a dominant cause of chronic liver disease, but the exact mechanism of progression from simple steatosis to nonalcoholic steatohepatitis (NASH) remains unknown. Here, we investigated the role of exosomes in NAFLD progression. Exosomes were isolate...
Enregistré dans:
| Auteurs principaux: | Young-Sun Lee, So Yeon Kim, Eunjung Ko, Jun-Hee Lee, Hyon-Seung Yi, Yang Jae Yoo, Jihye Je, Sang Jun Suh, Young Kul Jung, Ji Hoon Kim, Yeon Seok Seo, Hyung Joon Yim, Won-Il Jeong, Jong Eun Yeon, Soon Ho Um, Kwan Soo Byun |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Nature Portfolio
2017
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/fc2211e42e4b41eeac53d974a0fc5a60 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Evaluation of the severity of nonalcoholic fatty liver disease through analysis of serum exosomal miRNA expression.
par: Jeong-An Gim, et autres
Publié: (2021) -
Circulating miRNA is a useful diagnostic biomarker for nonalcoholic steatohepatitis in nonalcoholic fatty liver disease
par: Tae Hyung Kim, et autres
Publié: (2021) -
Hepatocyte-derived exosomal miR-27a activateshepatic stellate cells through the inhibitionof PINK1-mediated mitophagy in MAFLD
par: Xin Luo, et autres
Publié: (2021) -
Hepatic stellate cells secrete Ccl5 to induce hepatocyte steatosis
par: Byeong-Moo Kim, et autres
Publié: (2018) -
RORα Enhances Lysosomal Acidification and Autophagic Flux in the Hepatocytes
par: Hyeon‐Ji Kim, et autres
Publié: (2021)