Esophageal Pressure and Clinical Assessments in the Gastroesophageal Reflux Disease Patients with Laryngopharyngeal Reflux Disease

Laryngopharyngeal reflux disease (LPRD) might be associated with reflux symptoms, and its severity is correlated with the Reflux Symptoms Index. Diagnosis is often challenging because of a lack of accurate diagnostic tools. Although an association between LPRD and gastroesophageal reflux disease (GE...

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Autores principales:	Yung-An Tsou, Sheng-Hwa Chen, Wen-Chieh Wu, Ming-Hsui Tsai, David Bassa, Liang-Chun Shih, Wen-Dien Chang
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	laryngopharyngeal reflux disease gastroesophageal reflux disease esophageal pressure Medicine R
Acceso en línea:	https://doaj.org/article/fc33c303c8ee44af9cbb9126bf2b5d70
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spelling	oai:doaj.org-article:fc33c303c8ee44af9cbb9126bf2b5d702021-11-25T18:01:02ZEsophageal Pressure and Clinical Assessments in the Gastroesophageal Reflux Disease Patients with Laryngopharyngeal Reflux Disease10.3390/jcm102252622077-0383https://doaj.org/article/fc33c303c8ee44af9cbb9126bf2b5d702021-11-01T00:00:00Zhttps://www.mdpi.com/2077-0383/10/22/5262https://doaj.org/toc/2077-0383Laryngopharyngeal reflux disease (LPRD) might be associated with reflux symptoms, and its severity is correlated with the Reflux Symptoms Index. Diagnosis is often challenging because of a lack of accurate diagnostic tools. Although an association between LPRD and gastroesophageal reflux disease (GERD) exists, the extent to which esophageal pressure changes in patients with LPRD with GERD has been unknown. Therefore, this study surveys the clinical assessments and extent of esophageal pressure changes in LRPD patients with various GERD severities, and compares esophageal sphincter pressures between ages, genders, and body mass index (BMI). This observational study assessed patients with LPRD and GERD. High-resolution esophageal manometry was used to gather data pertaining to the area pressure on the upper esophageal sphincter (UES) and lower esophageal sphincter (LES), and the correlation between such pressure and symptom severity was determined. We compared the esophageal pressure of different UES and LES levels in the following categories: gender, age, BMI, and GERD severity. We analyzed correlations between esophageal pressure and clinical assessments among 90 patients with throat globus with laryngitis with LPRD. LPRD was measured using laryngoscopy, and GERD was measured using esophagoscopy and 24 h PH monitoring. There were no significant differences in the clinical assessments among the four grades of GERD. The LPRD patients with serious GERD had a lower UES and LES pressure. The lowest pressure and longer duration of LES and UES were also observed among patients with LPRD of grade D GERD. No significant differences in UES and LES pressures among ages, genders, or BMIs were noted.Yung-An TsouSheng-Hwa ChenWen-Chieh WuMing-Hsui TsaiDavid BassaLiang-Chun ShihWen-Dien ChangMDPI AGarticlelaryngopharyngeal reflux diseasegastroesophageal reflux diseaseesophageal pressureMedicineRENJournal of Clinical Medicine, Vol 10, Iss 5262, p 5262 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	laryngopharyngeal reflux disease gastroesophageal reflux disease esophageal pressure Medicine R
spellingShingle	laryngopharyngeal reflux disease gastroesophageal reflux disease esophageal pressure Medicine R Yung-An Tsou Sheng-Hwa Chen Wen-Chieh Wu Ming-Hsui Tsai David Bassa Liang-Chun Shih Wen-Dien Chang Esophageal Pressure and Clinical Assessments in the Gastroesophageal Reflux Disease Patients with Laryngopharyngeal Reflux Disease
description	Laryngopharyngeal reflux disease (LPRD) might be associated with reflux symptoms, and its severity is correlated with the Reflux Symptoms Index. Diagnosis is often challenging because of a lack of accurate diagnostic tools. Although an association between LPRD and gastroesophageal reflux disease (GERD) exists, the extent to which esophageal pressure changes in patients with LPRD with GERD has been unknown. Therefore, this study surveys the clinical assessments and extent of esophageal pressure changes in LRPD patients with various GERD severities, and compares esophageal sphincter pressures between ages, genders, and body mass index (BMI). This observational study assessed patients with LPRD and GERD. High-resolution esophageal manometry was used to gather data pertaining to the area pressure on the upper esophageal sphincter (UES) and lower esophageal sphincter (LES), and the correlation between such pressure and symptom severity was determined. We compared the esophageal pressure of different UES and LES levels in the following categories: gender, age, BMI, and GERD severity. We analyzed correlations between esophageal pressure and clinical assessments among 90 patients with throat globus with laryngitis with LPRD. LPRD was measured using laryngoscopy, and GERD was measured using esophagoscopy and 24 h PH monitoring. There were no significant differences in the clinical assessments among the four grades of GERD. The LPRD patients with serious GERD had a lower UES and LES pressure. The lowest pressure and longer duration of LES and UES were also observed among patients with LPRD of grade D GERD. No significant differences in UES and LES pressures among ages, genders, or BMIs were noted.
format	article
author	Yung-An Tsou Sheng-Hwa Chen Wen-Chieh Wu Ming-Hsui Tsai David Bassa Liang-Chun Shih Wen-Dien Chang
author_facet	Yung-An Tsou Sheng-Hwa Chen Wen-Chieh Wu Ming-Hsui Tsai David Bassa Liang-Chun Shih Wen-Dien Chang
author_sort	Yung-An Tsou
title	Esophageal Pressure and Clinical Assessments in the Gastroesophageal Reflux Disease Patients with Laryngopharyngeal Reflux Disease
title_short	Esophageal Pressure and Clinical Assessments in the Gastroesophageal Reflux Disease Patients with Laryngopharyngeal Reflux Disease
title_full	Esophageal Pressure and Clinical Assessments in the Gastroesophageal Reflux Disease Patients with Laryngopharyngeal Reflux Disease
title_fullStr	Esophageal Pressure and Clinical Assessments in the Gastroesophageal Reflux Disease Patients with Laryngopharyngeal Reflux Disease
title_full_unstemmed	Esophageal Pressure and Clinical Assessments in the Gastroesophageal Reflux Disease Patients with Laryngopharyngeal Reflux Disease
title_sort	esophageal pressure and clinical assessments in the gastroesophageal reflux disease patients with laryngopharyngeal reflux disease
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/fc33c303c8ee44af9cbb9126bf2b5d70
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Esophageal Pressure and Clinical Assessments in the Gastroesophageal Reflux Disease Patients with Laryngopharyngeal Reflux Disease

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