Aflatoxin-induced TP53 R249S mutation in hepatocellular carcinoma in Thailand: association with tumors developing in the absence of liver cirrhosis.

Aflatoxin-induced TP53 R249S mutation in hepatocellular carcinoma in Thailand: association with tumors developing in the absence of liver cirrhosis.

Primary Liver Cancer (PLC) is the leading cause of death by cancer among males in Thailand and the 3(rd) among females. Most cases are hepatocellular carcinoma (HCC) but cholangiocarcinomas represent between 4 and 80% of liver cancers depending upon geographic area. Most HCC are associated with chro...

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Autores principales: Stephanie Villar, Sandra Ortiz-Cuaran, Behnoush Abedi-Ardekani, Doriane Gouas, Andre Nogueira da Costa, Amelie Plymoth, Thiravud Khuhaprema, Anant Kalalak, Suleeporn Sangrajrang, Marlin D Friesen, John D Groopman, Pierre Hainaut
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/fc3484b9932c4b9f8a845aa4c22b0066
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