Prognostic relevance of the hexosamine biosynthesis pathway activation in leiomyosarcoma

Prognostic relevance of the hexosamine biosynthesis pathway activation in leiomyosarcoma

Abstract Metabolic reprogramming of tumor cells and the increase of glucose uptake is one of the hallmarks of cancer. In order to identify metabolic pathways activated in leiomyosarcoma (LMS), we analyzed transcriptomic profiles of distinct subtypes of LMS in several datasets. Primary, recurrent and...

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Autores principales: Angela Tolwani, Magdalena Matusiak, Nam Bui, Erna Forgó, Sushama Varma, Lucia Baratto, Andrei Iagaru, Alexander J. Lazar, Matt van de Rijn, Joanna Przybyl
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Genetics
QH426-470
Acceso en línea:https://doaj.org/article/fc3aae85255741adb708ed42e7403540
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