Rational engineering of recombinant picornavirus capsids to produce safe, protective vaccine antigen.
Foot-and-mouth disease remains a major plague of livestock and outbreaks are often economically catastrophic. Current inactivated virus vaccines require expensive high containment facilities for their production and maintenance of a cold-chain for their activity. We have addressed both of these majo...
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Main Authors: | Claudine Porta, Abhay Kotecha, Alison Burman, Terry Jackson, Jingshan Ren, Silvia Loureiro, Ian M Jones, Elizabeth E Fry, David I Stuart, Bryan Charleston |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2013
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Online Access: | https://doaj.org/article/fc4b6b80395249348ee566851c53b6d1 |
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