Rational engineering of recombinant picornavirus capsids to produce safe, protective vaccine antigen.

Foot-and-mouth disease remains a major plague of livestock and outbreaks are often economically catastrophic. Current inactivated virus vaccines require expensive high containment facilities for their production and maintenance of a cold-chain for their activity. We have addressed both of these majo...

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Bibliographic Details
Main Authors: Claudine Porta, Abhay Kotecha, Alison Burman, Terry Jackson, Jingshan Ren, Silvia Loureiro, Ian M Jones, Elizabeth E Fry, David I Stuart, Bryan Charleston
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
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Online Access:https://doaj.org/article/fc4b6b80395249348ee566851c53b6d1
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