Time-programmable drug dosing allows the manipulation, suppression and reversal of antibiotic drug resistance in vitro

It is unclear whether strategies involving antibiotic cycling can efficiently control the emergence of antibiotic-resistant bacteria. Here, Yoshidaet al. show that the evolution of multi-drug-resistant bacteria in vitrocan be manipulated by administering pairs of antibiotics and switching between th...

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Autores principales:	Mari Yoshida, Sabrina Galiñanes Reyes, Soichiro Tsuda, Takaaki Horinouchi, Chikara Furusawa, Leroy Cronin
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/fc4eceff007845fe96615de8ddda818c
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spelling	oai:doaj.org-article:fc4eceff007845fe96615de8ddda818c2021-12-02T15:38:42ZTime-programmable drug dosing allows the manipulation, suppression and reversal of antibiotic drug resistance in vitro10.1038/ncomms155892041-1723https://doaj.org/article/fc4eceff007845fe96615de8ddda818c2017-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms15589https://doaj.org/toc/2041-1723It is unclear whether strategies involving antibiotic cycling can efficiently control the emergence of antibiotic-resistant bacteria. Here, Yoshidaet al. show that the evolution of multi-drug-resistant bacteria in vitrocan be manipulated by administering pairs of antibiotics and switching between them.Mari YoshidaSabrina Galiñanes ReyesSoichiro TsudaTakaaki HorinouchiChikara FurusawaLeroy CroninNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Mari Yoshida Sabrina Galiñanes Reyes Soichiro Tsuda Takaaki Horinouchi Chikara Furusawa Leroy Cronin Time-programmable drug dosing allows the manipulation, suppression and reversal of antibiotic drug resistance in vitro
description	It is unclear whether strategies involving antibiotic cycling can efficiently control the emergence of antibiotic-resistant bacteria. Here, Yoshidaet al. show that the evolution of multi-drug-resistant bacteria in vitrocan be manipulated by administering pairs of antibiotics and switching between them.
format	article
author	Mari Yoshida Sabrina Galiñanes Reyes Soichiro Tsuda Takaaki Horinouchi Chikara Furusawa Leroy Cronin
author_facet	Mari Yoshida Sabrina Galiñanes Reyes Soichiro Tsuda Takaaki Horinouchi Chikara Furusawa Leroy Cronin
author_sort	Mari Yoshida
title	Time-programmable drug dosing allows the manipulation, suppression and reversal of antibiotic drug resistance in vitro
title_short	Time-programmable drug dosing allows the manipulation, suppression and reversal of antibiotic drug resistance in vitro
title_full	Time-programmable drug dosing allows the manipulation, suppression and reversal of antibiotic drug resistance in vitro
title_fullStr	Time-programmable drug dosing allows the manipulation, suppression and reversal of antibiotic drug resistance in vitro
title_full_unstemmed	Time-programmable drug dosing allows the manipulation, suppression and reversal of antibiotic drug resistance in vitro
title_sort	time-programmable drug dosing allows the manipulation, suppression and reversal of antibiotic drug resistance in vitro
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/fc4eceff007845fe96615de8ddda818c
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Time-programmable drug dosing allows the manipulation, suppression and reversal of antibiotic drug resistance in vitro

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